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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Selenium Bioaccessibility and Speciation in Selenium-Enriched Lettuce: Investigation of the Selenocompounds Liberated after in Vitro Simulated Human Digestion Using Two-Dimensional HPLC-ICP-MS

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Author(s):
da Silva, Emanueli do Nascimento ; Aureli, Federica ; D'Amato, Marilena ; Raggi, Andrea ; Cadore, Solange ; Cubadda, Francesco
Total Authors: 6
Document type: Journal article
Source: Journal of Agricultural and Food Chemistry; v. 65, n. 14, p. 3031-3038, APR 12 2017.
Web of Science Citations: 15
Abstract

The evaluation of selenium-enriched vegetables as potential dietary sources of selenium, an essential element for humans, requires an assessment of the plant's accumulation ability as well as of the bioaccessibility and speciation of the accumulated selenium, which influence its biological effects in humans. Lettuce hydroponically grown at three selenite (SeVI)/selenate (SeIV) amendment levels was characterized accordingly. Selenium accumulation in lettuce leaves was greatest with Se(VI) amendment, whereas bioaccessibility was 70% on average in both cases. Selenium speciation in gastrointestinal hydrolysates, characterized by anion and cation exchange HPLC-ICP-MS, showed that Se(IV) was largely biotransformed into organoselenium metabolites, with selenomethionine accounting for 1/3 of the total detected species, whereas Se(VI) was incorporated as such in the edible portion of the plant, with only a small fraction (similar to,20%) converted into organic species. Taking into account both nutritional quality and safety, the Se(IV)-enriched lettuce appeared more favorable as a potential selenium source for human consumption. (AU)

FAPESP's process: 12/15020-4 - Bioaccessibility and bioavailability of nutrients and toxic elements in lettuce (Lactuca sativa)
Grantee:Emanueli Do Nascimento da Silva
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 14/15425-0 - Selenium biofortification of lettuce: study of selenium bioaccessibility and speciation in the edible portion of the plant
Grantee:Emanueli Do Nascimento da Silva
Support Opportunities: Scholarships abroad - Research Internship - Doctorate
FAPESP's process: 13/26855-2 - Evaluation of bioaccessible and bioavailable fractions of nutrients and contaminants in vegetables
Grantee:Solange Cadore
Support Opportunities: Regular Research Grants