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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

In situ effect of CPP-ACP chewing gum upon erosive enamel loss

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Author(s):
Barros de Alencar, Catarina Ribeiro ; de Oliveira, Gabriela Cristina ; Magalhaes, Ana Carolina ; Rabelo Buzalaf, Marilia Afonso ; de Andrade Moreira Machado, Maria Aparecida ; Honorio, Heitor Marques ; Rios, Daniela
Total Authors: 7
Document type: Journal article
Source: Journal of Applied Oral Science; v. 25, n. 3, p. 258-264, MAY-JUN 2017.
Web of Science Citations: 1
Abstract

Abstract Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is able to increase salivary calcium and phosphate levels at an acidic pH. Previous studies demonstrated that a CPP-ACP chewing gum was able to enhance the re-hardening of erosion lesions, but could not diminish enamel hardness loss. Therefore, there is no consensus regarding the effectiveness of CPP-ACP on dental erosion. Objective This in situ study investigated the ability of a CPP-ACP chewing gum in preventing erosive enamel loss. Material and Methods: During three experimental crossover phases (one phase per group) of seven days each, eight volunteers wore palatal devices with human enamel blocks. The groups were: GI – Sugar free chewing gum with CPP-ACP; GII – Conventional sugar free chewing gum; and GIII – No chewing gum (control). Erosive challenge was extraorally performed by immersion of the enamel blocks in cola drink (5 min, 4x/day). After each challenge, in groups CPP and No CPP, volunteers chewed one unit of the corresponding chewing gum for 30 minutes. Quantitative analysis of enamel loss was performed by profilometry (µm). Data were analyzed by Repeated-Measures ANOVA and Tukey’s test (p<0.05). Results The use of chewing gum (CPP and No CPP) resulted in lower erosive enamel loss compared with the control group (p<0.05). CPP-ACP chewing gum (CPP) did not improve the protection against erosive enamel loss compared with conventional chewing gum (No CPP) (p>0.05). Conclusion The CPP-ACP chewing gum was not able to enhance the anti-erosive effect of conventional chewing gum against enamel loss. (AU)

FAPESP's process: 11/16326-7 - In situ effect of chewing gum containning casein phosphopeptide - amorphous calcium phosphate (cpp-acp)on dental erosion
Grantee:Catarina Ribeiro Barros de Alencar
Support Opportunities: Scholarships in Brazil - Master