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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Preconception maternal immunization to dust mite inhibits the type I hypersensitivity response of offspring

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Author(s):
Victor, J. R. ; Fusaro, A. E. ; Duarte, A. J. de S. ; Sato, M. N. [4]
Total Authors: 4
Document type: Journal article
Source: Journal of Allergy and Clinical Immunology; v. 111, n. 2, p. 269-277, Feb. 2004.
Field of knowledge: Biological Sciences - Immunology
Abstract

The maternal immunologic experience associated with early life exposure to allergens might contribute to the development of allergy during infancy. We sought to analyze the effect of the mother's immunization before conception with the dust mite Dermatophagoides pteronyssinus on the allergen priming and hypersensitivity response in early immunized offspring. The kinetics of D pteronyssinus immunization were observed from newborn to adult age, and the secondary response to D pteronyssinus was followed in offspring immunized in early life. Maternal immunization to D pteronyssinus seems to protect offspring from the development of allergy. (AU)