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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Integration host factor is important for biofilm formation by Salmonella enterica Enteritidis

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Leite, Bruna ; Werle, Catierine Hirsch ; do Carmo, Camila Pinheiro ; Nobrega, Diego Borin ; Milanez, Guilherme Paier ; Culler, Hebert Fabricio ; Sircili, Marcelo Palma ; Alvarez-Martinez, Cristina E. ; Brocchi, Marcelo
Total Authors: 9
Document type: Journal article
Source: PATHOGENS AND DISEASE; v. 75, n. 6 AUG 2017.
Web of Science Citations: 3

Salmonella enterica Enteritidis forms biofilms and survives in agricultural environments, infecting poultry and eggs. Bacteria in biofilms are difficult to eradicate compared to planktonic cells, causing serious problems in industry and public health. In this study, we evaluated the role of ihfA and ihfB in biofilm formation by S. enterica Enteritidis by employing different microbiology techniques. Our data indicate that ihf mutant strains are impaired in biofilm formation, showing a reduction in matrix formation and a decrease in viability and metabolic activity. Phenotypic analysis also showed that deletion of ihf causes a deficiency in curli fimbriae expression, cellulose production and pellicle formation. These results show that integration host factor has an important regulatory role in biofilm formation by S. enterica Enteritidis. (AU)

FAPESP's process: 12/25426-8 - Biofilm formation in different null mutants of Salmonella enterica
Grantee:Bruna Leite Simioni
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 12/10608-3 - Phenotypic and genotypic profile of antimicrobial resistance in Klebsiella pneumoniae, Salmonella enterica and coagulase-negative Staphylococcus
Grantee:Diego Borin Nóbrega
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/05382-6 - Virulence evaluation and Differential gene expression in vivo of Salmonella enterica mutants for nucleoid associated proteins
Grantee:Guilherme Paier Milanez
Support type: Scholarships in Brazil - Doctorate