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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Assessment of skin pigmentation by confocal microscopy: Influence of solar exposure and protection habits on cutaneous hyperchromias

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Author(s):
Martini, Ana Paula M. ; Mercurio, Daiane G. ; Maia Campos, Patricia M. B. G.
Total Authors: 3
Document type: Journal article
Source: Journal of Cosmetic Dermatology; v. 16, n. 3, p. 364-369, SEP 2017.
Web of Science Citations: 2
Abstract

BackgroundCutaneous hyperchromias are disorders of skin pigmentation involving an increase of melanin production and its irregular accumulation in skin cells. It is known that the use of sunscreens helps to prevent changes in the skin pigmentation pattern, but the structural and morphological alterations that occur in the different types of hyperpigmentations need better elucidation. ObjectiveTo assess the influence of solar exposure and protection habits on the pattern of skin pigmentation using reflectance confocal microscopy (RCM). MethodsForty volunteers aged 18-39 years with skin hyperpigmentation participated in the study. Skin characterization was performed by imaging techniques and by assessing the habits of solar exposure and protection by applying questionnaires to the volunteers. RCM was used to record sequences of confocal sections at areas of interest and to examine cell shape and brightness in the basal cell layer of the lesion and in normal perilesional skin. Furthermore, high-resolution images were obtained for analysis of the spots. ResultsSunlight influences the number and location of spots as the face of volunteers with higher solar exposure was covered with spots, whereas volunteers with less exposure had fewer spots located in the nose and cheeks region due to greater exposure of these areas to the sun. ConclusionThe data showed the importance of sun protection for preventing changes in the pattern of skin pigmentation, and RCM proved to be an important tool for skin characterization. (AU)

FAPESP's process: 14/26988-5 - Characterization of the skin pigmentation pattern and evaluation of photoprotectors on the reduction of cutaneous hyperchromias
Grantee:Ana Paula Martins Martini
Support Opportunities: Scholarships in Brazil - Scientific Initiation