Short-Term High- and Moderate-Intensity Training Modifies Inflammatory and Metabolic Factors in Response to Acute Exercise

Author(s)

Lira, Fabio Santos ^[1] ; dos Santos, Thaislaine ^[1] ; Caldeira, Renan Santos ^[1] ; Inoue, Daniela S. ^[1] ; Panissa, Valeria L. G. ^[2] ; Cabral-Santos, Carolina ^[1] ; Campos, Eduardo Z. ^[3] ; Rodrigues, Bruno ^[4] ; Monteiro, Paula A. ^[1]

Affiliation

^[1] State Univ Unesp, Sch Technol & Sci, Dept Phys Educ, Exercise & Immunometab Res Grp, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Sch Phys Educ & Sport, Dept Sport, Sao Paulo - Brazil

^[3] Univ Fed Pernambuco, Dept Phys Educ, Recife, PE - Brazil

^[4] Univ Estadual Campinas, Fac Phys Educ, Campinas, SP - Brazil

• Document type: Journal article
• Source: FRONTIERS IN PHYSIOLOGY; v. 8, OCT 31 2017.
• Web of Science Citations: 9

Abstract

Purpose: To compare the acute and chronic effects of high intensity intermittent training (HIIT) and steady state training (SST) on the metabolic profile and inflammatory response in physically active men. Methods: Thirty recreationally active men were randomly allocated to a control group (n = 10), HIIT group (n = 10), or SST group (n = 10). For 5 weeks, three times per week, subjects performed HIIT (5 km 1-min at 100% of maximal aerobic speed interspersed by 1-min passive recovery) or SST (5 km at 70% of maximal aerobic speed) while the control group did not perform training. Blood samples were collected at fasting (similar to 12 h), pre-exercise, immediately post, and 60 min post-acute exercise session (pre- and post-5 weeks training). Blood samples were analyzed for glucose, non-ester fatty acid (NEFA), and cytokine (IL-6, IL10, and TNIF-alpha) levels through a three-way analysis (group, period, and moment of measurement) with repeated measures in the second and third factors. Results: The results showed an effect of moment of measurement (acute session) with greater values to TN F-alpha and glucose immediately post the exercise when compared to pre exercise session, independently of group or training period. For IL-6 there was an interaction effect for group and moment of measurement (acute session) the increase occurred immediately post-exercise session and post-60 min in the HIIT group while in the SST the increase was observed only 60 min post, independently of training period. For IL-10, there was an interaction for training period (pre- and post-training) and moment of measurement (acute session), in which in pre-training, pre-exercise values were lower than immediately and 60 min post-exercise, in post-training period pre-exercise values were lower than immediately post-exercise and immediately post-exercise lower than 60 min post, it was also observed that values immediately post exercise were lower pre- than post-training, being all results independently of intensity (group). Conclusion: Our main result point to an interaction (acute and chronic) for IL-10 showing attenuation post-training period independent of exercise intensity. (AU)

• FAPESP's process: 15/12979-7 - High-intensity intermittent training and neuroendocrine regulation of adipose tissue depot: training volume effect
• Grantee: Renan Santos Caldeira
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 16/16712-8 - BDNF involvement in the function of lymphocytes of sedentary obese and trained: relationship with cognitive
• Grantee: Fábio Santos de Lira
• Support Opportunities: Regular Research Grants
• FAPESP's process: 15/11302-3 - Effect of intensity and time of exercise on appetite in overweight men
• Grantee: Valéria Leme Gonçalves Panissa
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 16/12145-1 - High-intensity intermittent training and anti-inflammatory response
• Grantee: Thaislaine dos Santos
• Support Opportunities: Scholarships in Brazil - Scientific Initiation