Multifunctional Hybrids Based on 2D Fluorinated Graphene Oxide and Superparamagnetic Iron Oxide Nanoparticles

Author(s)

Radhakrishnan, Sruthi ^[1] ; Sudeep, Parambath M. ^{[1, 2]} ; Park, Jun Hyoung ^[3] ; Woellner, Cristiano F. ^{[1, 4]} ; Maladonado, Kierstein ^[5] ; Galvao, Douglas S. ^[4] ; Kaipparettu, Benny Abraham ^{[3, 6]} ; Tiwary, Chandra Sekhar ^[1] ; Ajayan, Pulickel M. ^[1]

Affiliation

^[1] Rice Univ, Dept Mat Sci & Nano Engn, Houston, TX 77005 - USA

^[2] Univ Toronto, Dept Mech & Ind Engn, Toronto, ON M5S 3E3 - Canada

^[3] Baylor Coll Med, Dept Mol & Human Genet, Houston, TX 77030 - USA

^[4] State Univ Campinas UNICAMP, Appl Phys Dept, BR-13083859 Campinas, SP - Brazil

^[5] Univ Texas MD Anderson Canc Ctr, Small Anim Imaging Facil, Houston, TX 77030 - USA

^[6] Baylor Coll Med, Dan L Duncan Comprehens Canc Ctr, Houston, TX 77030 - USA

• Document type: Journal article
• Source: PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION; v. 34, n. 11 NOV 2017.
• Web of Science Citations: 2

Abstract

Carbon-based nanomaterials have garnered a lot of attention in the research of yesteryear. Here this study reports a composite based on fluorinated graphene oxide-a multifunctional subsidiary of graphene; and iron oxide nano-particles as a contrast agent for magnetic resonance imaging (MRI). Extensive structural and functional characterization is carried out to understand composite behavior toward biotoxicity and its performance as a contrast agent. The electron withdrawing fluorine group decreases the charge transfer to iron oxide increasing the magnetic saturation of the composite thus enhancing the contrast. The interaction of paramagnetic and superparamagnetic systems yields a superior contrast agent for MRI and fluorescent imaging. (AU)

• FAPESP's process: 13/08293-7 - CCES - Center for Computational Engineering and Sciences
• Grantee: Munir Salomao Skaf
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• FAPESP's process: 16/12340-9 - Structural and mechanical properties of carbon-based foams
• Grantee: Cristiano Francisco Woellner
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor