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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Healing at the Interface Between Autologous Block Bone Grafts and Recipient Sites Using n-Butyl-2-Cyanoacrylate Adhesive as Fixation: Histomorphometric Study in Rabbits

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Author(s):
De Santis, Enzo [1] ; Silva, Erick Ricardo [2] ; Carneiro Martins, Evandro Neto [2] ; Favero, Riccardo [1] ; Botticelli, Daniele [1] ; Xavier, Samuel Porfirio [2]
Total Authors: 6
Affiliation:
[1] ARDEC Acad, Ariminum Odontol, Rimini - Italy
[2] Univ Sao Paulo, Fac Ribeirao Preto, Dept CTBMF & Periodontia FORP, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF ORAL IMPLANTOLOGY; v. 43, n. 6, p. 447-455, DEC 2017.
Web of Science Citations: 2
Abstract

The aim of the present split-mouth (split-plot) study was to describe the sequential healing in the interface between autologous bone grafts and recipient parent bone, fixed using an n-butyl-2-cyanoacrylate adhesive with or without an additional titanium fixation screw. Bone grafts were collected from the calvaria and fixed to the lateral aspect of the mandible in 24 rabbits. The cortical layers of the recipient sites were perforated, and the grafts were randomly fixed using an n-butyl-2-cyanocrylate adhesive, either alone or in conjunction with a 1.5 mm x 6.0 mm titanium fixation screw. The animals were sacrificed after 3, 7, 20, and 40 days, and histomorphometric evaluations of the interface between graft and parent bone were performed. Only 2 of 6 grafts in each group were partially incorporated to the parent bone after 40 days of healing. The remaining grafts were separated from the parent bone by adhesive and connective tissue. It was concluded that the use of n-butyl-2-cyanoacrylate as fixation of an autologous bone graft to the lateral aspect of the mandible was able to maintain the fixation over time but did not incorporate the graft to the recipient sites. Use of fixation screws did not improve the healing. (AU)

FAPESP's process: 11/19479-9 - Onlay bone grafts fixation and integration with N-butil-2-cyanoacrilate, positional screws and lag screws: a histological, micro-CT and biomolecular study in rabbits
Grantee:Luiz Antonio Salata
Support Opportunities: Regular Research Grants