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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

High-level of resistance to beta-lactam and presence of beta-lactamases encoding genes in Ochrobactrum sp and Achromobacter sp isolated from soil

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Author(s):
Rueda Furlan, Joao Pedro [1] ; Stehling, Eliana Guedes [1]
Total Authors: 2
Affiliation:
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, Ribeirao Preto - Brazil
Total Affiliations: 1
Document type: Journal article
Source: JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE; v. 11, p. 133-137, DEC 2017.
Web of Science Citations: 4
Abstract

Objectives: Bacteria belonging to the genera Ochrobactrum and Achromobacter are bacteria considered opportunistic, causing infections mainly in immunocompromised patients. beta-lactamases are the main cause of resistance to beta-lactam antibiotics. This study aimed to investigate the antimicrobial resistance profile and the presence of beta-lactamases encoding genes in Ochrobactrum sp. and Achromobacter sp. isolated from Brazilian soils. Methods: Soil samples from the five regions of Brazil were collected for the isolation of bacteria, which were identified molecularly and then, the minimum inhibitory concentration and detection of beta-lactamases encoding genes were performed. Results: High-level of resistance to beta-lactam antibiotics and different beta-lactamases encoding genes were found (bla(CTX-M-Gp1), bla(SHV), bla(OXA-1-like) and bla(KPC)), including the first report of the presence of blaKPC in bacteria belonging to the genera Ochrobactrum and Achromobacter. Conclusion: The results showed that the bacteria from this study, belonging to genera Ochrobactrum and Achromobacter isolated from soil, harbor different b-lactamases encoding genes and can act as a reservoir of these genes. (C) 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 15/18990-2 - Investigation of quinolone resistance mechanisms in environmental bacterial isolates
Grantee:Eliana Guedes Stehling
Support Opportunities: Regular Research Grants