| Full text | |
| Author(s): |
Hazelden, Ian R.
[1]
;
Carmona, Rafaela C.
[1]
;
Langer, Thomas
[2]
;
Pringle, Paul G.
[1]
;
Bower, John F.
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon - England
[2] AstraZeneca, Pharmaceut Technol & Dev, Charter Way, Macclesfield SK10 2NA, Cheshire - England
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION; v. 57, n. 18, p. 5124-5128, APR 23 2018. |
| Web of Science Citations: | 8 |
| Abstract | |
Ligand-enabled aza-Heck cyclizations and cascades of N-(pentafluorobenzoyloxy)carbamates are described. These studies encompass the first examples of efficient non-biased 6-exo aza-Heck cyclizations. The methodology provides direct and flexible access to carbamate protected pyrrolidines and piperidines. (AU) | |
| FAPESP's process: | 16/00422-0 - Enantioselective construction of C-N bond by means of the Narasaka-Heck reaction |
| Grantee: | Rafaela Costa Carmona |
| Support Opportunities: | Scholarships abroad - Research Internship - Doctorate |