Ultralow Cost Electrochemical Sensor Made of Potato Starch and Carbon Black Nanoballs to Detect Tetracycline in Waters and Milk

Author(s)

Delgado, Karina P. ^[1] ; Raymundo-Pereira, Paulo A. ^[2] ; Campos, Anderson M. ^[3] ; Oliveira, Jr., Osvaldo N. ^[2] ; Janegitz, Bruno C. ^[1]

Affiliation

^[1] Univ Fed Sao Carlos, Dept Nat Sci Math & Educ, BR-13600970 Araras, SP - Brazil

^[2] Univ Sao Paulo, Sao Carlos Inst Phys, BR-13566590 Sao Carlos, SP - Brazil

^[3] Univ Sao Paulo, Sao Carlos Inst Chem, BR-13566590 Sao Carlos, SP - Brazil

• Document type: Journal article
• Source: Electroanalysis; v. 30, n. 9, p. 2153-2159, SEP 2018.
• Web of Science Citations: 3

Abstract

Detection of traces from pharmaceutical drugs such as antibiotics in drinking water and foodstuff is essential for guaranteeing human health in some environments, and this has to be done with low cost technologies to be widely deployed in public services and industry. In this paper, we describe an ultralow cost (<US\$0.005 per unit of sensing layer) electrochemical sensor to detect the antibiotic tetracycline, which is made of a homogeneous thin film of potato starch (PS) and carbon black (CB) deposited on glassy carbon electrodes (GCE). Detection of tetracycline was also performed in real samples consisting of tap water, river water, milk and in solutions prepared with commercial tablets of this medicine in the range between 5.0 and 120molL(-1), with a detection and quantification limit of 1.15 and 4.47molL(-1), respectively. The high sensitivity was attributed to the enhanced conductivity and larger surface area induced by incorporating the carbon black into potato starch. The CB-PS/GCE electrodes were reproducible and stable, thus serving as a generic platform for detection of other antibiotics and hormones whose redox potentials are similar to those of tetracycline. (AU)

• FAPESP's process: 16/01919-6 - Design and fabrication of nanostructured flexible devices for biomarkers detection
• Grantee: Paulo Augusto Raymundo Pereira
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 16/19885-0 - Determination of tetracycline in several samples using modified sensors with carbon black and potato starch
• Grantee: Karina Paes Delgado
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 13/14262-7 - Nanostructured films from biologically-relevant materials
• Grantee: Osvaldo Novais de Oliveira Junior
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 15/19099-2 - Development of electrochemical sensors and biosensors for different analytical purposes
• Grantee: Bruno Campos Janegitz
• Support Opportunities: Regular Research Grants