Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Dentoalveolar Abscesses Not Associated with Caries or Trauma: A Diagnostic Hallmark of Hypophosphatemic Rickets Initially Misdiagnosed as Hypochondroplasia

Full text
Author(s):
Yacarini Paredes, Silvia Elena [1] ; Bezerra Segato, Raquel Assed [1] ; Moreira, Leila Daher [2] ; Moreira, Alcides [2] ; Diaz Serrano, Kranya Victoria [1] ; Rodrigues, Clarissa Teles [3] ; Almeida, Luciana Yamamoto [4] ; Leon, Jorge Esquiche [5]
Total Authors: 8
Affiliation:
[1] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Pediat Dent, Sao Paulo, SP - Brazil
[2] Univ Grande Dourados UNIGRAN MS, Diagnost Bucal Ctr, Dourados - Brazil
[3] Univ Sao Paulo, Sch Dent Bauru, Dept Dent Endodont & Dent Mat, Sao Paulo, SP - Brazil
[4] Univ Sao Paulo, Ribeirao Preto Med Sch FMRP, Dept Clin Med, Div Hematol, Sao Paulo, SP - Brazil
[5] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Stomatol Publ Oral Hlth & Forens Dent, Oral Pathol, Sao Paulo, SP - Brazil
Total Affiliations: 5
Document type: Journal article
Source: Head and Neck Pathology; v. 12, n. 4, p. 604-609, DEC 2018.
Web of Science Citations: 0
Abstract

Hypophosphatemic rickets is a rare genetic disorder involving the regulation of fibroblast growth factor 23 (FGF23), a phosphaturic agent, clinically showing bowing of the legs, short stature and dentoalveolar abscesses. A 7-year-old boy, with previous hypochondroplasia diagnosis, was referred to our pediatric dentistry clinic presenting short stature, bone deformities and sinus tracts at deciduous teeth apex levels not related with trauma, restorations or dental caries. After deciduous teeth extraction, due to root resorption and mobility, light microscopy exhibited typical hypophosphatemic dentin, and micro-computed tomography revealed tubular clefts and porosities throughout the teeth. Laboratory tests confirmed the HR diagnosis, after which the treatment was initiated. (AU)

FAPESP's process: 16/11419-0 - Clinicopathological correlation of the degree of differentiation, tetraspanin expression, viral agents and cell proliferation in a large sample of squamous cell carcinoma of the head and neck region.
Grantee:Jorge Esquiche León
Support Opportunities: Regular Research Grants
FAPESP's process: 11/52090-8 - Comparative immunohistochemical analysis of dendritic cells, cytotoxic lymphocytes, and indolamine 2,3-dioxigenase expression in potentially malignant disorders and squamous cells carcinoma of the oral cavity and lower lip
Grantee:Jorge Esquiche León
Support Opportunities: Regular Research Grants