Alterations in brain connectivity due to plasticity and synaptic delay

Author(s)

Lameu, E. L. ^[1] ; Macau, E. E. N. ^{[1, 2]} ; Borges, F. S. ^[3] ; Iarosz, K. C. ^[3] ; Caldas, I. L. ^[3] ; Borges, R. R. ^[4] ; Protachevicz, P. R. ^[5] ; Viana, R. L. ^[6] ; Batista, A. M. ^{[7, 3, 5]}

Affiliation

^[1] Natl Inst Space Res, Sao Jose Dos Campos, SP - Brazil

^[2] Univ Fed Sao Paulo, Sao Jose Dos Campos - Brazil

^[3] Univ Sao Paulo, Inst Phys, Sao Jose Dos Campos - Brazil

^[4] Fed Technol Univ Parana, Dept Math, Ponta Grossa, PR - Brazil

^[5] Univ Estadual Ponta Grossa, Sci Postgrad, Ponta Grossa, PR - USA

^[6] Univ Fed Parana, Dept Phys, Curitiba, PR - Brazil

^[7] Univ Estadual Ponta Grossa, Dept Math & Stat, Ponta Grossa, PR - Brazil

• Document type: Journal article
• Source: European Physical Journal-Special Topics; v. 227, n. 5-6, p. 673-682, SEP 2018.
• Web of Science Citations: 1

Abstract

Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and synchronization in a neuronal network with synaptic plasticity. We build a network of Hodgkin-Huxley neurons, where the plasticity is given by the Hebbian rules. We verify that without time delay the synapses become regulated by both the nature (excitatory or inhibitory) and the frequency of the presynaptic and postsynaptic neuron. A presynaptic excitatory (inhibitory) neuron with higher (lower) frequency enhances the synaptic strength if the postsynaptic excitatory (inhibitory) neuron has lower (higher) frequency. When the delay is increased the network presents a non-trivial topology. Regarding the synchronization, only for small values of the synaptic delay this phenomenon is observed. (AU)

• FAPESP's process: 17/18977-1 - Analysis of Electrical Synapses Contribution in Neuronal Synchronization
• Grantee: Fernando da Silva Borges
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 17/20920-8 - Plasticity in neuronal networks
• Grantee: Kelly Cristiane Iarosz
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 16/23398-8 - Synaptic plasticity in neuronal networks with time delay
• Grantee: Ewandson Luiz Lameu
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 15/07311-7 - Dynamic behaviour of neural networks
• Grantee: Kelly Cristiane Iarosz
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 17/13502-5 - Synchronisation in time-delayed networks with synaptic plasticity
• Grantee: Ewandson Luiz Lameu
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 15/50122-0 - Dynamic phenomena in complex networks: basics and applications
• Grantee: Elbert Einstein Nehrer Macau
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 11/19296-1 - Nonlinear dynamics
• Grantee: Iberê Luiz Caldas
• Support Opportunities: Research Projects - Thematic Grants