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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Does enamel matrix derivative application improve clinical outcomes after semilunar flap surgery? A randomized clinical trial

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Franca-Grohmann, Isabela Lima [1] ; Menck Sangiorgio, Joao Paulo [1] ; Bueno, Manuela Rocha [1] ; Viana Casarin, Renato Correa [1] ; Silverio, Karina Gonzales [1] ; Nociti, Jr., Francisco Humberto [1] ; Casati, Marcio Zaffalon [1] ; Sallum, Enilson Antonio [1]
Total Authors: 8
[1] Univ Estadual Campinas, Dept Prosthodont & Periodont, Div Periodont, Piracicaba Dent Sch, Piracicaba, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: CLINICAL ORAL INVESTIGATIONS; v. 23, n. 2, p. 879-887, FEB 2019.
Web of Science Citations: 2

ObjectivesTo evaluate the treatment of gingival recessions by semilunar coronally positioned flap plus enamel matrix derivative (SCPF + EMD).Materials and methodsThirty patients with class I localized gingival recession were included. They were randomly allocated in two groups: SCPF + EMD and SCPF. Recession height (RH), recession width (RW), width of keratinized tissue (WKT), thickness of keratinized tissue (TKT), probing depth (PD), and clinical attachment level (CAL) were measured at baseline, 6 and 12months post-surgery. Patient/professional evaluation of esthetics and root sensitivity was performed.ResultsAfter 12months, mean root coverage was 1.980.33mm for SCPF + EMD (90.8614.69%) and 1.85 +/- 0.41mm (79.76 +/- 17.44%) for SCPF (p>0.05). The esthetic evaluation by the patient showed preference for SCPF + EMD. According to the professional evaluation (QCE), the use of EMD decreases the appearance of postoperative scar tissue line. There was a significant reduction in root hypersensitivity with no further complaints by the patients.Conclusions The addition of EMD provides significantly better esthetics to SCPF, according to patient and professional assessments. SCPF + EMD is effective but not superior to SCPF for root coverage, after 12months.Clinical relevance Previous clinical trials showed that the combination of EMD with coronally advanced flaps may enhance the outcome of root coverage. There is a lack of studies testing the combination of EMD with SCPF. The combination SCPF + EMD provides better esthetics when compared to the SCPF and is effective, but not superior, to SCPF for root coverage, after 12months.Trial registration: NCT02459704 (AU)

FAPESP's process: 13/13098-9 - Semilunar flap with or without enamel matrix derivative for the treatment of gingival recessions Miller Class I: a randomized controlled clinical trial
Grantee:Isabela Lima França Grohmann
Support type: Scholarships in Brazil - Master