A novel thread-based microfluidic device for capillary electrophoresis with capacitively coupled contactless conductivity detection

Author(s)

Quero, Reverson Fernandes ^[1] ; Bressan, Lucas Paines ^[1] ; Fracassi da Silva, Jose Alberto ^{[2, 1]} ; de Jesus, Dosil Pereira ^{[2, 1]}

Affiliation

^[1] Univ Estadual Campinas, UNICAMP, Inst Chem, POB 6154, BR-13083970 Campinas, SP - Brazil

^[2] Inst Nacl Ciencia & Tecnol Bioanalit, Campinas, SP - Brazil

• Document type: Journal article
• Source: SENSORS AND ACTUATORS B-CHEMICAL; v. 286, p. 301-305, MAY 1 2019.
• Web of Science Citations: 3

Abstract

This work describes a novel thread-based microfluidic device to perform capillary electrophoresis separation and capacitively coupled contactless conductivity detection. Polyester threads with a diameter of about 315 mu m were assembled (stretched) in a 3D-printed platform containing solution reservoirs and platinum electrodes. Separation of potassium, sodium, and lithium ions was achieved within 1 min with good peak resolutions and limits of detection close to 1 mu mol L-1. Inversion of the electroosmotic flow direction by adding a cationic surfactant in the running electrolyte was demonstrated. The applicability of the thread-based microfluidic devices was successfully evaluated by the determination of sodium and potassium ions in commercial samples of diet soft drinks. (AU)

• FAPESP's process: 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis
• Grantee: Marco Aurelio Zezzi Arruda
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 13/22127-2 - Development of novel materials strategic for integrated analytical devices
• Grantee: Lauro Tatsuo Kubota
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 18/06478-3 - Use of 3D Printing on the Fabrication of Microfluidic Devices
• Grantee: José Alberto Fracassi da Silva
• Support Opportunities: Regular Research Grants