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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evaluation of bone ingrowth into porous titanium implant: histomorphometric analysis in rabbits

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Author(s):
Luana Marotta Reis de Vasconcellos [1] ; Daniel Oliveira Leite [2] ; Fernanda Nascimento de Oliveira [3] ; Yasmin Rodarte Carvalho [4] ; Carlos Alberto Alves Cairo [5]
Total Authors: 5
Affiliation:
[1] Univ Estadual Paulista. Faculdade de Odontologia de São José dos Campos. Department of Oral Biosciences and Diagnosis - Brasil
[2] Univ Estadual Paulista. Faculdade de Odontologia de São José dos Campos. Department of Oral Biosciences and Diagnosis - Brasil
[3] Univ Estadual Paulista. Faculdade de Odontologia de São José dos Campos - Brasil
[4] Univ Estadual Paulista. Faculdade de Odontologia de São José dos Campos. Department of Oral Biosciences and Diagnosis - Brasil
[5] Comando-Geral de Tecnologia Aeroespacial. Air and Space Institute. Department of Materials - Brasil
Total Affiliations: 5
Document type: Journal article
Source: Brazilian Oral Research; v. 24, n. 4, p. 399-405, 2010-12-00.
Abstract

A porous material for bone ingrowth with adequate pore structure and appropriate mechanical properties has long been sought as the ideal bone-implant interface. This study aimed to assess in vivo the influence of three types of porous titanium implant on the new bone ingrowth. The implants were produced by means of a powder metallurgy technique with different porosities and pore sizes: Group 1 = 30 % and 180 µm; Group 2 = 30% and 300 µm; and Group 3 = 40% and 180 µm;. Six rabbits received one implant of each type in the right and left tibiae and were sacrificed 8 weeks after surgery for histological and histomorphometric analyses. Histological analysis confirmed new bone in contact with the implant, formed in direction of pores. Histomorphometric evaluation demonstrated that the new bone formation was statistically significantly lower in the group G1 than in group G3, (P = 0.023). Based on these results, increased porosity and pore size were concluded to have a positive effect on the amount of bone ingrowth. (AU)

FAPESP's process: 05/03709-4 - Study of porous implants osseointegration: analysis of bone growth in pores, resistance of implant-bone interface and mechanical property of porous titanium
Grantee:Luana Marotta Reis de Vasconcellos
Support Opportunities: Scholarships in Brazil - Post-Doctoral