Panel detection "human herpesvirus" by nested polymerase chain reaction in patient...
| Full text | |
| Author(s): |
Takahama Jr, Ademar
;
de Lima, Heliton Gustavo
[1]
;
Ito, Fabio Augusto
[1]
;
Ribeiro-Silva, Alfredo
[2]
;
Leon, Jorge Esquiche
[3]
Total Authors: 5
|
| Affiliation: | [1] Takahama Jr, Jr., Ademar, Univ Estadual Londrina, Dept Oral Med & Pediat Dent, Londrina - Brazil
[2] Univ Sao Paulo, Dept Pathol & Forens Med, Ribeirao Preto Med Sch, Ribeirao Preto - Brazil
[3] Univ Sao Paulo, Dept Stomatol Publ Oral Hlth & Forens Dent, Sch Dent Ribeirao Preto, Pathol, Ribeirao Preto - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY; v. 77, n. 5, p. 977-984, MAY 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
Epstein-Barr virus-positive mucocutaneous ulcer (EBVMCU) is characterized by cutaneous and/or mucosal ulcers in patients receiving immunosuppressive medication or with age-related immunosenescence. Its microscopic appearance often leads to a diagnostic challenge, sometimes mimicking an overt lymphoma. A 47-year-old woman, with a previous diagnosis of systemic lupus erythematosus, was referred for evaluation of a gingival ulcer, present for about 2 months and located in the maxillary peri-implant mucosa around implants, resembling peri-implantitis. An incisional biopsy was performed, and the microscopic evaluation showed a polymorphic infiltrate with some Reed-Sternberg-like cells. Immunohistochemistry showed positive findings for CD20, CD30, CD45, PAX-5, MUM-1, LMP-1 and EBER1/2, establishing the diagnosis of EBVMCU. After 2 months, total regression of the lesion was noted without any intervention. We discuss the possible association between the EBVMCU and systemic lupus erythematosus; to our knowledge, this is the first report of an EBVMCU simulating peri-implantitis. (C) 2019 American Association of Oral and Maxillofacial Surgeons (AU) | |
| FAPESP's process: | 16/11419-0 - Clinicopathological correlation of the degree of differentiation, tetraspanin expression, viral agents and cell proliferation in a large sample of squamous cell carcinoma of the head and neck region |
| Grantee: | Jorge Esquiche León |
| Support type: | Regular Research Grants |
| FAPESP's process: | 16/02713-2 - Effects of erlotinib and gefitinib therapy in combination with all-trans retinoic acid and arsenic trioxide in Acute Promyelocytic Leukemia: in vitro, ex vivo and murine experimental model studies |
| Grantee: | Luciana Yamamoto de Almeida |
| Support type: | Scholarships in Brazil - Post-Doctorate |