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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Unusual presentation of a disseminated oral HPV infection after combined antiretroviral therapy initiation

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Author(s):
Daniela Assis do Vale [1] ; Lais Magda Araújo Ferracini [2] ; Marcus Vinícius da Silva Rodrigues Bueno [3] ; Ana Carolina Mamana Fernandes Souza [4] ; Paulo Henrique Braz-Silva ; Karem López Ortega [6]
Total Authors: 6
Affiliation:
[1] Universidade de São Paulo. Faculdade de Odontologia. Departamento de Estomatologia - Brasil
[2] Universidade de São Paulo. Faculdade de Odontologia. Departamento de Estomatologia - Brasil
[3] Universidade de São Paulo. Faculdade de Odontologia. Departamento de Estomatologia - Brasil
[4] Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo. Laboratório de Virologia - Brasil
[6] Universidade de São Paulo. Faculdade de Odontologia. Departamento de Estomatologia - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Revista do Instituto de Medicina Tropical de São Paulo; v. 61, 2019-10-10.
Abstract

ABSTRACT HPV clinical manifestations have their characteristics modified by the use of combined antiretroviral therapy (cART), although its incidence is unaffected by cART. We report an unusual presentation of oral HPV infection and discuss an effective treatment for disseminated HPV lesions. A 52-year-old male of Asian-origin, HIV-seropositive, presented with extensive nodular lesions throughout the oral mucosa extending to the oropharyngeal region. Biopsy followed by histopathological examination and HPV genotyping were performed. The treatment was initiated with topical application of podophyllin and trichloroacetic acid. HPV lesions in oral mucosa are generally easy to handle. Extensive lesions can make it difficult to choose an effective treatment that meets the patient’s particularities and medication availability. (AU)

FAPESP's process: 15/07727-9 - Evaluation of immunoregulatory microenvironment of oral premalignant lesions, squamous cell carcinomas and oropharyngeal carcinomas related to HPV or not.
Grantee:Paulo Henrique Braz da Silva
Support Opportunities: Regular Research Grants