Development and evaluation of biogenic metal nanoparticles (silver, titanium and i...
| Full text | |
| Author(s): |
Guilger-Casagrande, Mariana
[1]
;
Germano-Costa, Tais
[1]
;
Pasquoto-Stigliani, Tatiane
[1]
;
Fraceto, Leonardo Fernandes
[2]
;
de Lima, Renata
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Sorocaba UNISO, Lab Evaluat Bioact & Toxicol Nanomat, Sorocaba, SP - Brazil
[2] State Univ Sao Paulo UNESP, Lab Environm Nanotechnol, Sorocaba, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | SCIENTIFIC REPORTS; v. 9, OCT 4 2019. |
| Web of Science Citations: | 0 |
| Abstract | |
Biogenic synthesis of silver nanoparticles employing fungi offers advantages, including the formation of a capping from fungal biomolecules, which provides stability and can contribute to biological activity. In this work, silver nanoparticles were synthesized using Trichoderma harzianum cultivated with (AgNP-TS) and without enzymatic stimulation (AgNP-T) by the cell wall of Sclerotinia sclerotiorum. The nanoparticles were evaluated for the control of S. sclerotiorum. The specific activity of the T. harzianum hydrolytic enzymes were determined in the filtrates and nanoparticles. Cytotoxicity and genotoxicity were also evaluated. Both the nanoparticles exhibited inhibitory activity towards S. sclerotiorum, with no new sclerotia development, however Ag NP-TS was more effective against mycelia! growth. Both the filtrates and the nanoparticles showed specific enzymatic activity. Low levels of cytotoxicity and genotoxicity were observed. This study opens perspectives for further exploration of fungal biogenic nanoparticles, indicating their use for the control of S. sclerotiorum and other agricultural pests. (AU) | |
| FAPESP's process: | 16/13692-6 - Silver biogenic nanoparticles based on Trichoderma harzianum: different synthesis conditions, evaluation of cyto/genotoxicity and inhibitory potential of Sclerotinia sclerotiorum |
| Grantee: | Mariana Guilger |
| Support type: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 17/13328-5 - Development and evaluation of biogenic metal nanoparticles (silver, titanium and iron) based on Trichoderma harzianum for agricultural application |
| Grantee: | Renata de Lima |
| Support type: | Regular Research Grants |
| FAPESP's process: | 17/21004-5 - Agriculture, micro/nanotechnology and environment: from evaluation of the mechanisms of action to studies of transport and toxicity |
| Grantee: | Leonardo Fernandes Fraceto |
| Support type: | Research Projects - Thematic Grants |