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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Impact of probiotics and prebiotics targeting metabolic syndrome

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Author(s):
Xavier-Santos, Douglas [1, 2, 3] ; Bedani, Raquel [1, 2] ; Lima, Egidio Dorea [4] ; Isay Saad, Susana Marta [1, 2]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Food Res Ctr, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Biochem & Pharmaceut Technol, Av Prof Lineu Prestes 580, B16, BR-05508000 Sao Paulo, SP - Brazil
[3] Univ Genoa, Pole Chem Engn, Dept Civil Chem & Environm Engn, Via Opera Pia 15, I-16145 Genoa - Italy
[4] Univ Sao Paulo, Univ Hosp, Av Prof Lineu Prestes 2565, BR-05508000 Sao Paulo, SP - Brazil
Total Affiliations: 4
Document type: Review article
Source: Journal of Functional Foods; v. 64, JAN 2020.
Web of Science Citations: 0
Abstract

Several studies are contributing to the better understanding of the impact of probiotics and prebiotics on the modulation of the intestinal microbiota and subsequent effects on the host's health. This review aimed to discuss the results of studies using different experimental models to evaluate the impact of the supplementation with probiotics and/or prebiotics on the different risk factors related to metabolic syndrome (MetS). A better understanding of the daily supplementation of probiotics and prebiotics regarding the mechanisms involved in the modulation of the intestinal microbiota and the immune system of patients suffering from this metabolic disorder is necessary to establish the efficiency of possible biomarkers that could contribute towards a health claim. Although the results might be promising, the functionality of probiotics and prebiotics on the intestinal microbiota and its relationship with MetS are still poorly understood to indicate their consumption for prevention and management of MetS in clinical practice. (AU)

FAPESP's process: 13/07914-8 - FoRC - Food Research Center
Grantee:Bernadette Dora Gombossy de Melo Franco
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 13/04422-7 - Synbiotic aerated dessert: diet product development and evaluation of the intake effects in individuals with metabolic syndrome.
Grantee:Douglas Xavier dos Santos
Support Opportunities: Scholarships in Brazil - Doctorate