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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Longitudinal visual acuity development in ZIKV-exposed children

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Author(s):
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Lima, Diego da Silva [1] ; Portnoi Baran, Luiz Claudio [1] ; Hamer, Russell David [1, 2] ; da Costa, Marcelo Fernandes [1] ; Vidal, Kallene Summer [1] ; Damico, Francisco Max [1, 3] ; Salgueiro Barboni, Mirella Telles [1, 4] ; Rodrigues de Matos Franca, Valtenice de Cassia [1] ; Gomes Martins, Cristiane Maria [1] ; Tabares, Heydi Segundo [1] ; Dias, Sarah Leonardo [1] ; Silva, Leonardo Aparecido [1] ; Decleva, Diego [1] ; Zatz, Mayana [5] ; Antunes Pascalicchio Bertozzi, Ana Paula [6] ; Gazeta, Rosa Estela [6] ; Passos, Saulo Duarte [6] ; Ventura, Dora Fix [1]
Total Authors: 18
Affiliation:
[1] Univ Sao Paulo, Inst Psychol, Dept Expt Psychol, Sao Paulo - Brazil
[2] Florida Atlantic Univ, Dept Psychol, Boca Raton, FL 33431 - USA
[3] Univ Sao Paulo, Sao Paulo Med Sch, Dept Ophthalmol, Sao Paulo - Brazil
[4] Semmelweis Univ, Dept Ophthalmol, Budapest - Hungary
[5] Univ Sao Paulo, Stem Cell & Human Genome Res Ctr, Biosci Inst, Sao Paulo - Brazil
[6] Jundiai Med Sch, Jundiai - Brazil
Total Affiliations: 6
Document type: Journal article
Source: JOURNAL OF AAPOS; v. 24, n. 1 FEB 2020.
Web of Science Citations: 0
Abstract

PURPOSE To follow the visual acuity development of children exposed to or infected with the Zika virus (ZIKV) during gestation and to relate potential visual acuity deficits to their clinical condition. METHODS In this prospective study, visual acuity was measured via Teller Acuity Cards in three groups of children: (1) those with confirmed ZIKV exposure (ZE) through the mother only, (2) those with confirmed infection (ZI), and (3) unaffected controls. Visual acuity was measured 2-4 times in each child during the first 30 months of age. RESULTS The study included 22 children in the ZE group, 11 in the ZI group, and 27 controls. Visual acuity developed normally in both patient groups, including infected patients (ZI) that did not manifest clinical symptoms. In a small subgroup of patients with characteristics consistent with congenital Zika syndrome (CZS), visual acuity was within normative values, with the exception of single child with chorioretinal atrophy. CONCLUSIONS In this southeastern Brazil study cohort, visual acuity development seemed to progress normally in infected children without CZS symptoms. (AU)

FAPESP's process: 14/26818-2 - Development and implementation of visual evaluation methods: clinical applications and animal models
Grantee:Dora Selma Fix Ventura
Support type: Research Projects - Thematic Grants
FAPESP's process: 16/22007-5 - Optimization of the visual functional ability in patients with macular diseases using visual training programs
Grantee:Mirella Telles Salgueiro Barboni
Support type: Scholarships abroad - Research
FAPESP's process: 16/14793-0 - Relationship between gestational Zika virus infection (ZIKV) and alterations in visual acuity and color perception in infants up to three years old
Grantee:Luiz Claudio Portnoi Baran
Support type: Scholarships in Brazil - Master
FAPESP's process: 13/05942-4 - Visual and cognitive assessment of children in the first three years of life that were affected by bilateral congenital cataracts
Grantee:Valtenice de Cássia Rodrigues de Matos França
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 16/24631-8 - Implications of Zika virus exposure during gestation for the development of visual function
Grantee:Diego da Silva Lima
Support type: Scholarships in Brazil - Master
FAPESP's process: 17/16948-4 - Impact of different types of modification of the gene for dystrophin in the vision of patients with muscular dystrophy
Grantee:Leonardo Aparecido Silva
Support type: Scholarships in Brazil - Master