| Full text | |
| Author(s): |
Ciolac, Emmanuel Gomes
[1, 2]
;
Rodrigues da Silva, Jose Messias
[1, 2, 3]
;
Vieira, Rodolfo Paula
[4, 5, 6, 7]
Total Authors: 3
|
| Affiliation: | [1] Sao Paulo State Univ UNESP, Exercise & Chron Dis Res Lab ECDR, Dept Phys Educ, Sch Sci, Bauru, SP - Brazil
[2] Sao Paulo State Univ UNESP, Postgrad Program Movement Sci, Dept Phys Educ, Sch Sci, Bauru, SP - Brazil
[3] Vieira, Rodolfo Paula, Brazilian Inst Teaching \& Res Pulm \& Exercise Imm, Sao Jose Dos Campos, SP, Brazil.Ciolac, Emmanuel Gomes, Sao Paulo State Univ UNESP, Exercise & Chron Dis Res Lab ECDR, Dept Phys Educ, Sch Sci, Bauru, SP - Brazil
[4] Brazilian Inst Teaching & Res Pulm & Exercise Imm, Sao Jose Dos Campos, SP - Brazil
[5] Univ Brasil, Postgrad Program Bioengn & Biomed Engn, Sao Paulo - Brazil
[6] Anhembi Morumbi Univ, Sch Med, Sao Jose Dos Campos, SP - Brazil
[7] Univ Fed Sao Paulo, Postgrad Program Sci Human Movement & Reghabilita, Santos, SP - Brazil
Total Affiliations: 7
|
| Document type: | Journal article |
| Source: | JOURNAL OF PHYSICAL ACTIVITY & HEALTH; v. 17, n. 6, p. 662-672, JUN 2020. |
| Web of Science Citations: | 0 |
| Abstract | |
Background: The progressive dysfunction of the immune system during aging appears to be involved in the pathogenesis of several age-related disorders. However, regular physical exercise can present ``antiaging{''} effects on several physiological systems. Methods: A narrative review of studies investigating the chronic effects of exercise and physical activity on the immune system and its association with age-related chronic diseases was carried out according to the guidelines for writing a narrative review. Results: There is compelling evidence suggesting that age-related immune system alterations play a key role on the pathophysiology of atherosclerosis, hypertension, chronic heart failure, type 2 diabetes, obesity, arthritis, and chronic obstructive pulmonary disease. On the other hand, the regular practice of physical activity appears to improve most of the inflammatory/ immunological processes involved in these diseases. Conclusion: Epidemiological, experimental, and clinical studies permit us to affirm that regular physical activity improves immunomodulation and may play a key role in the prevention and treatment of several age-related chronic diseases. However, further studies are needed to better describe the prophylactic and therapeutic effects of physical exercise in specific organs of older individuals, as well as the mechanisms involved in such response. (AU) | |
| FAPESP's process: | 12/02409-0 - Effects of water based vs. land based exercise training on bone mass, physical fitness and body composition of heart transplant recipients |
| Grantee: | Emmanuel Gomes Ciolac |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 17/25648-4 - Effect of heated water-based versus land-based exercise training on hemodynamic variables, functional capacity and quality of life in older hypertensive individuals |
| Grantee: | Emmanuel Gomes Ciolac |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 12/15165-2 - Role of purinergic signaling and of SOCS-JAK-STAT signaling in the antiinflammatory effects of aerobic training in experimental models of asma and in asthmatic individuals |
| Grantee: | Rodolfo de Paula Vieira |
| Support Opportunities: | Research Grants - Young Investigators Grants |