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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Latitudinal diversity gradient and cetaceans from the perspective of MHC genes

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Author(s):
Andreani, Maria Luiza [1] ; Nery, Mariana F. [4]
Total Authors: 2
Affiliation:
[1] Univ Estadual Campinas UNICAMP, Dept Genet Evolucao Microbiol & Imunol, Lab Genom Evolut, Inst Biol, Rua Monteiro Lobato, 255, Cidade Univ, IB, Bloco H, BR-13083862 Campinas, SP - Brazil
[2] Nery, Mariana F., Univ Estadual Campinas UNICAMP, Dept Genet Evolucao Microbiol \& Imunol, Lab Genom Evolut, Inst Biol, Rua Monteiro Lobato,255,Cidade Univ,IB,Bloco H, BR-13083862 Campinas, SP, Brazil.Andreani, Maria Luiza, Univ Estadual Campinas UNICAMP, Dept Genet Evolucao Microbiol & Imunol, Lab Genom Evolut, Inst Biol, Rua Monteiro Lobato, 255, Cidade Univ, IB, Bloco H, BR-13083862 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: IMMUNOGENETICS; v. 72, n. 6-7 JUN 2020.
Web of Science Citations: 0
Abstract

Pathogen diversity is a key source of selective pressure on immune system genes, shaping molecular evolution mainly on widely distributed or migratory organisms such as cetaceans. Here, we investigated the effects of latitudinal span migration, different biomes occupation, and pathogen-mediated selection on MHC DQB locus divergence on cetaceans. We applied some evolutionary genetics methods using a dataset of 15 species and 121 sequences, and we found a trend on greater MHC divergence on tropical species when compared with either temperate or migratory species. In addition, oceanic cetaceans exhibit greater MHC divergence. Here, we show that, despite there was a correlation between the diversity of MHC DQB alleles with the distribution of organisms, the pattern of diversity found is not completely explained by pathogenic pressure, suggesting that other factors must be investigated for a better understanding of the processes related to the diversity of MHC in cetaceans. (AU)

FAPESP's process: 15/18269-1 - Using comparative genomics to understand convergent evolution of mammals: tracking the molecular footprints of the marine and riverine environment colonisation
Grantee:Mariana Freitas Nery
Support Opportunities: Research Grants - Young Investigators Grants