Effect of 12 Weeks of Endurance Training Combined with Creatine Supplement, Photobiomodulation Therapy, or Both on Performance and Muscle Damage in Rats

Author(s)

Malta, Elvis de Souza ^[1] ; Ferraresi, Cleber ^[2] ; Monte, Marina Gaiato ^[3] ; de Poli, Rodrigo Araujo Bonetti ^[1] ; Bjordal, Jan Magnus ^[4] ; Lopes-Martins, Rodrigo alvaro Brandao ^[5] ; Marcos, Rodrigo Labat ^[6] ; Zagatto, Alessandro Moura ^[1] ; Carvalho, Rodrigo Leal de Paiva ^[1]

Affiliation

^[1] Sao Paulo State Univ UNESP, Postgrad Program Movement Sci, Lab Physiol & Sport Performance LAFIDE, Dept Phys Educ, Ave Eng Luiz Edmundo Carrijo Coube, BR-17033360 Bauru, SP - Brazil

^[2] Univ Brasil, Postgrad Program Biomed Engn, Sao Paulo, SP - Brazil

^[3] UNESP, Med Sch, Postgrad Program Pathophysiol, Med Clin, Botucatu, SP - Brazil

^[4] Univ Bergen, Dept Global Publ Hlth & Primary Care, Physiotherapy Res Grp, Bergen - Norway

^[5] Univ Vale Paraiba UNIVAP, Lab Biophoton & Expt Therapeut, Inst Res & Dev, Sao Jose Dos Campos, SP - Brazil

^[6] UNINOVE Appl Biophoton Hlth Sci, Sao Paulo, SP - Brazil

• Document type: Journal article
• Source: PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY; v. 38, n. 12 JUN 2020.
• Web of Science Citations: 0

Abstract

Background:Photobiomodulation therapy (PBMT) and creatine (Cr) intake have been used in conjunction with heavy training, but little is known about their possible effects during a long-term training program. Objective:We assessed long-term use of PBMT and Cr in an exercise training program. Methods:Twenty-five male Wistar rats weighing similar to 300 g were randomly allocated to one of five groups: a nontraining control group, a training group, a training group receiving Cr, a training group receiving PBMT, and a training group receiving both PBMT and Cr. The training program consisted of 12 weeks of daily swimming training. PBMT was delivered in six points with a laser device (808 nm, 100 mW, 30 s per point of irradiation, 3 J, 75 J/cm(2)). Results:All training groups showed significantly higher peak force and longer time to 50% decay of force, and lower creatine kinase (CK) levels than the nontraining control group, thus confirming the benefit of the training program. In all outcomes related to muscle performance, the groups receiving PBMT with or without Cr supplement performed significantly better (p < 0.05) peak force and time of force decay during an electrical stimulation protocol than all the other groups. In addition, CK levels were also significantly lower for the PBMT groups than for the other groups. Conclusions:We conclude that PBMT alone or in conjunction with Cr supplement during a 12-week training program resulted in significantly better muscle performance and lower levels of CK, a biochemical marker of muscle damage. (AU)

• FAPESP's process: 17/21724-8 - Impact of cold-water immersion regular use after high-intensity interval training sessions on muscle repair, muscle adaptation and running performance
• Grantee: Elvis de Souza Malta
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 19/17445-1 - Influence of high intensity interval training on time to exhaustion during a supramaximal effort: biomolecular and neuromuscular responses
• Grantee: Rodrigo de Araujo Bonetti de Poli
• Support Opportunities: Scholarships in Brazil - Doctorate