Epidemiological and clinical characteristics of the COVID-19 epidemic in Brazil

Author(s):Show less -

de Souza, William Marciel ^[1] ; Buss, Lewis Fletcher ^[2] ; Candido, Darlan da Silva ^{[3, 2]} ; Carrera, Jean-Paul ^{[3, 4]} ; Li, Sabrina ^[5] ; Zarebski, Alexander E. ^[3] ; Pereira, Rafael Henrique Moraes ^[6] ; Prete, Jr., Carlos A. ^[7] ; de Souza-Santos, Andreza Aruska ^[8] ; Parag, Kris V. ^[9] ; Belotti, Maria Carolina T. D. ^[7] ; Vincenti-Gonzalez, Maria F. ^[10] ; Messina, Janey ^{[5, 11]} ; da Silva Sales, Flavia Cristina ^[2] ; Andrade, Pamela dos Santos ^[2] ; Nascimento, Vitor Heloiz ^[7] ; Ghilardi, Fabio ^[2] ; Abade, Leandro ^[3] ; Gutierrez, Bernardo ^{[3, 12]} ; Kraemer, Moritz U. G. ^{[13, 3, 14]} ; Braga, Carlos K. V. ^[6] ; Aguiar, Renato Santana ^[15] ; Alexander, Neal ^[16] ; Mayaud, Philippe ^[17] ; Brady, Oliver J. ^{[15, 18]} ; Marcilio, Izabel ^[19] ; Gouveia, Nelson ^[20] ; Li, Guangdi ^[21] ; Tami, Adriana ^[10] ; de Oliveira, Silvano Barbosa ^[22] ; Porto, Victor Bertollo Gomes ^[22] ; Ganem, Fabiana ^[22] ; de Almeida, Walquiria Aparecida Ferreira ^[22] ; Fantinato, Francieli Fontana Sutile Tardetti ^[22] ; Macario, Eduardo Marques ^[23] ; de Oliveira, Wanderson Kleber ^[23] ; Nogueira, Mauricio L. ^[24] ; Pybus, Oliver G. ^[3] ; Wu, Chieh-Hsi ^[25] ; Croda, Julio ^{[23, 26, 27, 28]} ; Sabino, Ester C. ^[2] ; Faria, Nuno Rodrigues ^{[3, 2, 9]}

Affiliation:Show less -

^[1] Univ Sao Paulo, Fac Med Ribeirao Preto, Ctr Pesquisa Virol, Ribeirao Preto - Brazil

^[2] Univ Sao Paulo, Fac Med, Inst Med Trop, Sao Paulo - Brazil

^[3] Univ Oxford, Dept Zool, Oxford - England

^[4] Gorgas Mem Inst Hlth Studies, Dept Res Virol & Biotechnol, Panama City - Panama

^[5] Univ Oxford, Sch Geog & Environm, Oxford - England

^[6] Inst Appl Econom Res, IPEA, Brasilia, DF - Brazil

^[7] Univ Sao Paulo, Escola Politecn, Sao Paulo - Brazil

^[8] Univ Oxford, Latin Amer Ctr, Brazilian Studies Programme, Oxford - England

^[9] Imperial Coll London, MRC Centre Global Infect Dis Anal, IDEA, London - England

^[10] Univ Groningen, Univ Med Ctr Groningen, Dept Med Microbiol & Infect Prevent, Groningen - Netherlands

^[11] Univ Oxford, Oxford Sch Global & Area Studies, Oxford - England

^[12] Univ San Francisco Quito USFQ, Sch Biol & Environm Sci, Quito - Ecuador

^[13] Boston Childrens Hosp, Boston, MA - USA

^[14] Harvard Univ, Harvard Med Sch, Boston, MA - USA

^[15] Univ Fed Minas Gerais, Dept Genet Ecol & Evolucao, Inst Ciencias Biol, Belo Horizonte, MG - Brazil

^[16] Univ Fed Minas Gerais, Dept Infect Dis Epidemiol, MRC Tropical Epidemiol, Fac Epidemiol & Population Hlth, London Sch Hyg &, London - England

^[17] London Sch Hyg & Trop Med, Fac Epidemiol & Populat Hlth, Dept Clin Res, London - England

^[18] London Sch Hyg & Trop Med, Ctr Math Modelling Infect Dis, Dept Infect Dis Epidemiol, London - England

^[19] Univ Sao Paulo, Nucleo Vigilancia Epidmiol Hosp Clin, Fac Med, Sao Paulo - Brazil

^[20] Univ Sao Paulo, Fac Med, Dept Med Prevent, Sao Paulo - Brazil

^[21] Cent South Univ, Xiangya Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Fac Med, Changsha - Peoples R China

^[22] Brazilian Minist Hlth, Dept Immunizat & Communicable Dis, Secretariat Hlth Surveillance, Brasilia - Brazil

^[23] Brazilian Minist Hlth, Secretariat Hlth Surveillance, Brasilia, DF - Brazil

^[24] Fac Med Sao Jose Rio Preto, Sao Jose Do Rio Preto - Brazil

^[25] Univ Southampton, Math Sci, Southampton - England

^[26] Fundacao Univ Fed Grande Dourados, Lab Pesquisa Ciencias Saude, Dourados - Brazil

^[27] Fundacao Oswaldo Cruz, Campo Grande - Brazil

^[28] Yale Univ, Yale Sch Publ Hlth, Dept Epidmiol Microbial Dis, New Haven, CT - USA

• Document type: Journal article
• Source: NATURE HUMAN BEHAVIOUR; v. 4, n. 8 JUL 2020.
• Web of Science Citations: 0

Abstract

Brazil has one of the fastest-growing COVID-19 epidemics in the world. De Souza et al. report epidemiological, demographic and clinical findings for COVID-19 cases in the country during the first 3 months of the epidemic. The first case of COVID-19 was detected in Brazil on 25 February 2020. We report and contextualize epidemiological, demographic and clinical findings for COVID-19 cases during the first 3 months of the epidemic. By 31 May 2020, 514,200 COVID-19 cases, including 29,314 deaths, had been reported in 75.3% (4,196 of 5,570) of municipalities across all five administrative regions of Brazil. TheR(0)value for Brazil was estimated at 3.1 (95% Bayesian credible interval = 2.4-5.5), with a higher median but overlapping credible intervals compared with some other seriously affected countries. A positive association between higher per-capita income and COVID-19 diagnosis was identified. Furthermore, the severe acute respiratory infection cases with unknown aetiology were associated with lower per-capita income. Co-circulation of six respiratory viruses was detected but at very low levels. These findings provide a comprehensive description of the ongoing COVID-19 epidemic in Brazil and may help to guide subsequent measures to control virus transmission. (AU)

• FAPESP's process: 17/13981-0 - Characterization, genomics and diagnostic of viruses with importance for public health in Brazil by high throughput sequencing
• Grantee: William Marciel de Souza
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/24251-9 - Multi-omic approaches for the study of Chikungunya disease
• Grantee: William Marciel de Souza
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 18/12579-7 - ELIOT: enabling technologies for IoT
• Grantee: Vitor Heloiz Nascimento
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 18/14389-0 - Brazil-UK Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE)
• Grantee: Ester Cerdeira Sabino
• Support Opportunities: Research Projects - Thematic Grants