| Full text | |
| Author(s): |
Campos, Estefania V. R.
[1]
;
Pereira, Anderson E. S.
[2]
;
de Oliveira, Jhones Luiz
[2]
;
Carvalho, Lucas Braganca
[2]
;
Guilger-Casagrande, Mariana
[3]
;
de Lima, Renata
[3]
;
Fraceto, Leonardo Fernandes
[2]
Total Authors: 7
|
| Affiliation: | [1] Fed Univ ABC, Human & Nat Sci Ctr, Ave Estados, 5001 Bl A, T3 Lab 503-3 Bangu, Santo Andre, SP - Brazil
[2] Sao Paulo State Univ UNESP, Inst Sci & Technol, Sorocaba, SP - Brazil
[3] Univ Sorocaba, Rodovia Raposo Tavares Km 92, 5, Sorocaba, SP - Brazil
Total Affiliations: 3
|
| Document type: | Review article |
| Source: | JOURNAL OF NANOBIOTECHNOLOGY; v. 18, n. 1 SEP 5 2020. |
| Web of Science Citations: | 39 |
| Abstract | |
Incidents of viral outbreaks have increased at an alarming rate over the past decades. The most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread around the world and shown R(0)values from 2.2 to 2.68. However, the ratio between mortality and number of infections seems to be lower in this case in comparison to other human coronaviruses (such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)). These outbreaks have tested the limits of healthcare systems and have posed serious questions about management using conventional therapies and diagnostic tools. In this regard, the use of nanotechnology offers new opportunities for the development of novel strategies in terms of prevention, diagnosis and treatment of COVID-19 and other viral infections. In this review, we discuss the use of nanotechnology for COVID-19 virus management by the development of nano-based materials, such as disinfectants, personal protective equipment, diagnostic systems and nanocarrier systems, for treatments and vaccine development, as well as the challenges and drawbacks that need addressing. (AU) | |
| FAPESP's process: | 17/21004-5 - Agriculture, micro/nanotechnology and environment: from evaluation of the mechanisms of action to studies of transport and toxicity |
| Grantee: | Leonardo Fernandes Fraceto |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 19/05100-0 - Evaluation of the biological activity of topical formulations of budesonide in inflammatory skin models |
| Grantee: | Estefânia Vangelie Ramos Campos |
| Support Opportunities: | Scholarships abroad - Research Internship - Post-doctor |
| FAPESP's process: | 18/21142-1 - Encapsulation of Bacillus thuringiensis (Bacillales: Bacillaceae) in polymeric microparticles and association with nanoencapsulated chemical agent: evaluation of biological activity and mechanisms of action |
| Grantee: | Jhones Luiz de Oliveira |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 18/23608-8 - Development of labelled nanopesticides aiming studies of mechanism of action and toxicity |
| Grantee: | Lucas Bragança de Carvalho |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 20/05816-2 - Study of the capping of biogenic nanoparticles and their correlation with toxicity and activity in the control of phytopathogens |
| Grantee: | Mariana Guilger Casagrande |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 17/24402-1 - pH AND TEMPERATURE SENSITIVE DRUG NANOCARRIERS FOR SKIN APPLICATIONS |
| Grantee: | Estefânia Vangelie Ramos Campos |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |