Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Magnetic solid-phase extraction of gingerols in ginger containing products

Full text
Author(s):
Akamine, Lidia Akemi [1] ; Medina, Deyber Arley Vargas [1] ; Lancas, Fernando Mauro [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Inst Chem Sao Carlos, Sao Carlos, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Talanta; v. 222, JAN 15 2021.
Web of Science Citations: 0
Abstract

In this study, a graphene oxide/magnetite (GO-Fe3O4) nanocomposite was synthesized and used as a sorbent in the magnetic solid-phase extraction (MSPE) of gingerols from fresh ginger rhizomes, ginger extracts, commercial tea samples, ginger candies, thermogenic supplements, and tonic water. An MSPE method was developed, and the main influencing parameters in the sample preparation process were investigated. After GO-Fe3O4 based MSPE, 6-gingerol, 8-gingerol, and 10-gingerol were determined by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The whole GO-Fe3O4-MSPE-LC-MS/MS method proved high selectivity and consistent analytical confidence. The limits of detection (LOD) ranged between 2 and 3 mu g L-1. Intraday and inter-day RSDs fluctuated between 1.7 -13.4% and 0.4-10.9%, respectively. Weighted calibration revealed good linearity within the studied range (5-200 mu g L-1) and guaranteed appropriate accuracy (relative residues < 25%). MSPE with GO-Fe3O4 demonstrated to be a practical, fast, efficient, high-throughput, and environmental-friendly sample preparation technique for determining of gingerols in commercial products, and its hyphenation with LC-MS/MS analysis yield a valuable analytical tool for the confident quality control of commercial ginger-containing products. (AU)

FAPESP's process: 17/02147-0 - Single drop chromatography and its coupling to mass spectrometry: instrumental strategies, development of materials, automation and analytical applications
Grantee:Fernando Mauro Lanças
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 10/19910-9 - Development of green chemistry strategies on chromatography and application to the evaluation of antibiotics degradation in wastewaters by fixed-bed anaerobic bioreactors
Grantee:Alvaro José dos Santos Neto
Support Opportunities: Regular Research Grants
FAPESP's process: 19/22724-7 - Novel instrumental approaches for automated and miniaturized analytical methods for the detection of organic compounds by liquid chromatography coupled to mass spectrometry
Grantee:Deyber Arley Vargas Medina
Support Opportunities: Scholarships in Brazil - Post-Doctoral