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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

One Health Approach to Leishmaniases: Understanding the Disease Dynamics through Diagnostic Tools

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Hong, Ahyun [1] ; Zampieri, Ricardo Andrade [1] ; Shaw, Jeffrey Jon [2] ; Floeter-Winter, Lucile Maria [1] ; Laranjeira-Silva, Maria Fernanda [1]
Total Authors: 5
[1] Univ Sao Paulo, Inst Biosci, Dept Physiol, BR-05508090 Sao Paulo - Brazil
[2] Univ Sao Paulo, Inst Biomed Sci, Dept Parasitol, BR-05508000 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Review article
Source: PATHOGENS; v. 9, n. 10 OCT 2020.
Web of Science Citations: 0

Leishmaniases are zoonotic vector-borne diseases caused by protozoan parasites of the genus Leishmania that affect millions of people around the globe. There are various clinical manifestations, ranging from self-healing cutaneous lesions to potentially fatal visceral leishmaniasis, all of which are associated with different Leishmania species. Transmission of these parasites is complex due to the varying ecological relationships between human and/or animal reservoir hosts, parasites, and sand fly vectors. Moreover, vector-borne diseases like leishmaniases are intricately linked to environmental changes and socioeconomic risk factors, advocating the importance of the One Health approach to control these diseases. The development of an accurate, fast, and cost-effective diagnostic tool for leishmaniases is a priority, and the implementation of various control measures such as animal sentinel surveillance systems is needed to better detect, prevent, and respond to the (re-)emergence of leishmaniases. (AU)

FAPESP's process: 17/23933-3 - Identification and characterization of membrane proteins involved in iron transport and metabolism in Leishmania
Grantee:Maria Fernanda Laranjeira da Silva
Support type: Research Grants - Young Investigators Grants
FAPESP's process: 18/23512-0 - The Leishmania-host relationship from the ‘omics’ perspective
Grantee:Lucile Maria Floeter-Winter
Support type: Research Projects - Thematic Grants