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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Serological evidence of Mayaro virus infection in blood donors from sao Carlos, sao Paulo, Brazil

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Author(s):
Romeiro, Marilia Farignoli [1] ; Fumagalli, Marcilio Jorge [1] ; dos Anjos Souza, Ana Beatriz [1, 2] ; Moraes Figueiredo, Luiz Tadeu [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Virol Res Ctr, Ribeirao Preto Med Sch, Ribeirao Preto, SP - Brazil
[2] Banco Sangue Irmandade Santa Casa Misericordia Sa, Sao Carlos, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Transactions of the Royal Society of Tropical Medicine and Hygiene; v. 114, n. 9, p. 693-696, SEP 2020.
Web of Science Citations: 1
Abstract

Background: Human infections by Mayaro virus (MAYV) occur by insect bites upon exposure to rural or sylvatic areas. Information regarding MAYV transmission is Limited due to a Lack of commercial diagnostic assays and diagnostic confusion on account of similarities of clinical signs with other co-circulating arboviral diseases. Methods: A serological survey of MAYV and Chikunguya virus (CHIKV) antibodies was performed by ELISA. Between 2017 and 2018, 5608 blood donor samples were tested. Results: Specific IgM and IgG antibodies to MAYV were detected respectively in 36 and 11 samples, indicating a total seroprevalence of approximately 0.83%. Neutralization activity was observed in two IgG positive sera. Additionally, eight distinct samples had IgM antibodies to CHIKV alone. Conclusions: Our data suggest previously unreported circulation of MAYV in Sao Carlos city, from southeastern Brazil. (AU)

FAPESP's process: 16/01414-1 - Production of recombinant viral antigenic peptides and development of methods for serological diagnosis of infections by Chikungunya, Mayaro and Zika viruses
Grantee:Marcilio Jorge Fumagalli
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 14/02438-6 - Studies with Bunyaviridae that produce human disease
Grantee:Luiz Tadeu Moraes Figueiredo
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 14/20851-8 - Study about Alphavirus and Flavivirus infections in samples of blood bank
Grantee:Marilia Farignoli Romeiro
Support Opportunities: Scholarships in Brazil - Doctorate