Nanogap-based all-electronic DNA sequencing devices using MoS2 monolayers

Author(s)

Perez, A. ^[1] ; Amorim, Rodrigo G. ^[2] ; Villegas, Cesar E. P. ^{[3, 4]} ; Rocha, Alexandre R. ^[1]

Affiliation

^[1] Univ Estadual Paulista UNESP, Inst Fis TeoHca, Rua Dr Bento T Ferraz 271, BR-01140070 Sao Paulo, SP - Brazil

^[2] Univ Fed Fluminense, Dept Fis, Rio De Janeiro - Brazil

^[3] Univ Privada Norte, Dept Ciencias, Lima 15434 - Peru

^[4] Univ Nacl Mayor San Marcos, Fac Ciencias Fis, Lima 15081 - Peru

• Document type: Journal article
• Source: Physical Chemistry Chemical Physics; v. 22, n. 46, p. 27053-27059, DEC 14 2020.
• Web of Science Citations: 1

Abstract

The realization of nanopores in atom-thick materials may pave the way towards electrical detection of single biomolecules in a stable and scalable manner. In this work, we theoretically study the potential of different phases of MoS2 nanogaps to act as all-electronic DNA sequencing devices. We carry out simulations based on density functional theory and the non-equilibrium Green's function formalism to investigate the electronic transport across the device. Our results suggest that the 1T `-MoS2 nanogap structure is energetically more favorable than its 2H counterpart. At zero bias, the changes in the conductance of the 1T `-MoS2 device can be well distinguished, making possible the selectivity of the DNA nucleobases. Although the conductance fluctuates around the resonances, the overall results suggest that it is possible to distinguish the four DNA bases for energies close to the Fermi level. (AU)

• FAPESP's process: 16/01343-7 - ICTP South American Institute for Fundamental Research: a regional center for theoretical physics
• Grantee: Nathan Jacob Berkovits
• Support Opportunities: Special Projects
• FAPESP's process: 17/02317-2 - Interfaces in materials: electronic, magnetic, structural and transport properties
• Grantee: Adalberto Fazzio
• Support Opportunities: Research Projects - Thematic Grants