Experimental self-etching resin infiltrants on the treatment of simulated carious white spot lesions

Author(s)

Wang, Linda ^[1] ; Carvalho de Almendra Freitas, Maria Cristina ^{[1, 2]} ; Prakki, Anuradha ^[3] ; Mosquim, Victor ^[1] ; Miranda Gonzalez, Alejandra Hortencia ^[4] ; Rios, Daniela ^[5] ; Honorio, Heitor Marques ^[5]

Affiliation

^[1] Univ Sao Paulo, Baum Sch Dent, Dept Operat Dent Endodont & Dent Mat, Bauru, SP - Brazil

^[2] DeVry Educ Grp, DeVry FACID, Teresina, PI - Brazil

^[3] Univ Toronto, Fac Dent, Restorat Dept, Toronto, ON - Canada

^[4] Univ North Parana, Sch Dent, Dept Restorat Dent, Londrina, Parana - Brazil

^[5] Univ Sao Paulo, Bauru Sch Dent, Dept Pediat Dent Orthodont & Publ Hlth, Bauru, SP - Brazil

• Document type: Journal article
• Source: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS; v. 113, JAN 2021.
• Web of Science Citations: 0

Abstract

Objectives: To evaluate the penetration depth (mu m) of experimental resin infiltrants containing different percentages of triethylene glycol dimethacrylate (TEGDMA) and phosphoric acid 2-hydroxyethyl methacrylate ester (PAM) in artificial carious white spot lesions (WSL). Methods: WSL were produced in 65 bovine flat enamel specimens by pH cycling protocol, which were treated with either Icon (control) or experimental acidic infiltrants based on different percentages of TEGDMA and PAM monomers (acidic), and their association or not with previous acid-etching with phosphoric acid. Ten readings using Confocal Laser Scanning Microscopy were conducted on each specimen and the penetration depth was calculated from the surface until the deepest point with the fluorescent dye Rhodamine B (0.02 mg/mL). The pH and the viscosity of the experimental infiltrants were also tested. Data were statistically analyzed with two-way ANOVA and Tukey tests (alpha < 0.05). Results: The material factor and the interaction material{*}acid-etching were statistically significant. The lowest penetration depth was observed for the samples treated with the commercial infiltrant after etching with 15% hydrochloric acid. When specimens were pre-treated with PA, highest penetration was seen for specimens treated with 100% TEGDMA, which differed from all other groups. The lowest penetration was seen for those treated with 50:50 TEGDMA:PAM infiltrants. When specimens were not previously etched, highest penetration was seen for Icon, which differed only from those treated with 25% TEGDMA 75% PAM, where the lowest values were seen. The values of viscosity increased and the pH decreased with the addition of PAM in the infiltrant formulations. Conclusion: the association between TEGDMA and PAM seems to allow similar infiltration depth reached by Icon infiltrant without acid etching the enamel surface. (AU)

• FAPESP's process: 12/18579-2 - Effect of a resin infiltrant on white spot lesions treatment: in vitro, in situ and in vivo analyses
• Grantee: Maria Cristina Carvalho de Almendra Freitas
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 12/13160-3 - Effect of addition of fluorescent agent (Rodhamine B) to no-simplified dentin bonding agents: analisys of physical-mechanical properties
• Grantee: Linda Wang
• Support Opportunities: Regular Research Grants
• FAPESP's process: 13/23310-5 - Evaluation of the permeability of experimental resin infiltrants on the treatment of artificial white spot lesions
• Grantee: Maria Cristina Carvalho de Almendra Freitas
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate