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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Strategies for Cancer Treatment Based on Photonic Nanomedicine

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Author(s):
de Oliveira, Sueli Aparecida [1] ; Borges, Roger [2] ; dos Santos Rosa, Derval [1] ; de Souza, Ana Carolina Santos [2] ; Seabra, Amedea B. [2] ; Baino, Francesco [3] ; Marchi, Juliana [2]
Total Authors: 7
Affiliation:
[1] Fed Univ ABC, Ctr Engn Modelagem & Ciencias Sociais Aplicadas, Ave Estados 5001, BR-09210580 Santo Andre, SP - Brazil
[2] Fed Univ ABC, Ctr Ciencias Nat & Humanas, Ave Estados 5001, BR-09210580 Santo Andre, SP - Brazil
[3] Politecn Torino, Inst Mat Phys & Engn, Dept Appl Sci & Technol, I-10129 Turin - Italy
Total Affiliations: 3
Document type: Review article
Source: MATERIALS; v. 14, n. 6 MAR 2021.
Web of Science Citations: 0
Abstract

Traditional cancer treatments, such as surgery, radiotherapy, and chemotherapy, are still the most effective clinical practice options. However, these treatments may display moderate to severe side effects caused by their low temporal or spatial resolution. In this sense, photonic nanomedicine therapies have been arising as an alternative to traditional cancer treatments since they display more control of temporal and spatial resolution, thereby yielding fewer side effects. In this work, we reviewed the challenge of current cancer treatments, using the PubMed and Web of Science database, focusing on the advances of three prominent therapies approached by photonic nanomedicine: (i) photothermal therapy; (ii) photodynamic therapy; (iii) photoresponsive drug delivery systems. These photonic nanomedicines act on the cancer cells through different mechanisms, such as hyperthermic effect and delivery of chemotherapeutics and species that cause oxidative stress. Furthermore, we covered the recent advances in materials science applied in photonic nanomedicine, highlighting the main classes of materials used in each therapy, their applications in the context of cancer treatment, as well as their advantages, limitations, and future perspectives. Finally, although some photonic nanomedicines are undergoing clinical trials, their effectiveness in cancer treatment have already been highlighted by pre-clinical studies. (AU)

FAPESP's process: 16/16512-9 - Development of a hydrogel-based delivery system for release of biocompatible glasses ions and drug as support in treatment of bone cancer and subsequent bone regeneration
Grantee:Juliana Marchi
Support type: Regular Research Grants