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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

imeric naphthochromenes and other constituents from Sinningia allagophylla (Gesneriaceae

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Author(s):
Verdan, Maria Helena [1, 2] ; Winiewski, Vanessa [1] ; Scharf, Dilamara R. [1, 3] ; Salvador, Marcos Jose [4] ; de Sa, Eduardo L. [1] ; Stefanello, Maria Elida A. [1]
Total Authors: 6
Affiliation:
[1] Univ Fed Parana, Dept Chem, Ctr Politecn, POB 19081, BR-81530900 Curitiba, PR - Brazil
[2] Fed Univ Grande Dourados UFGD, Postgrad Program Chem, POB 364, BR-79804970 Dourados, MS - Brazil
[3] Univ Blumenau FURB, Chem Dept, Campus 2, BR-89030000 Blumenau, SC - Brazil
[4] Univ Campinas UNICAMP, Inst Biol, Dept Plant Biol, POB 6109, BR-13083971 Campinas, SP - Brazil
Total Affiliations: 4
Document type: Journal article
Source: PHYTOCHEMISTRY LETTERS; v. 42, p. 104-108, APR 2021.
Web of Science Citations: 0
Abstract

Sinningia allagophylla, found in Brazil, Paraguay and Argentina, is used by the Brazilian population as diuretic, febrifuge, depurative, and tonic. We present the isolation of nine compounds (1-9) from its tubers, four of them being new: two dimeric naphthochromenes, allagophylldimer D (1) and allagophylldimer E (2); a coumarin, 6,8dimethoxybenzocoumarin (3); and a naphthoquinone-derivative, allagophyllone (4). The known compounds were identified as ?-isodunnione (5), warmingiin A (6), warmingiin B (7), cleroindicin B (8), and cleroindicin C (9). All compounds were analyzed by 1D and 2D NMR, and HRMS spectra were recorded for the new compounds. Additionally, conformational analyses were carried on compounds 1 and 2. Compound 5 had been previously obtained only by synthesis, and its complete NMR data are presented here. (AU)

FAPESP's process: 06/06079-4 - Search of antioxidants and antimicrobials in Gomphreneae tribe species
Grantee:Marcos José Salvador
Support Opportunities: Regular Research Grants
FAPESP's process: 12/09101-1 - Investigation of treatment with 24-epibrassinolide in plant development, profile of volatile constituents and biological activities of essential oils from Cymbopogon citratus, Cymbopogon flexuosus and Mentha pulegium
Grantee:Marcos José Salvador
Support Opportunities: Regular Research Grants
FAPESP's process: 15/03726-8 - Integrated chemical and biological study in the search for bioactive substances in plants* and development of analytical procedures. *(Amaranthaceae, Gesneriaceae, Myrtaceae e Annonaceae)
Grantee:Marcos José Salvador
Support Opportunities: Regular Research Grants
FAPESP's process: 17/03598-5 - Preventive effect of Ilex paraguariensis preparations (chimarrão, terere and mate tea) against damages caused by chronic ethanol consumption: comparative analysis of preparation technology, chemical profile and evaluation of therapeutic effect and safety
Grantee:Mariana Mesquita Fonseca
Support Opportunities: Scholarships in Brazil - Doctorate