Reviewing research on the synthesis of CALB-catalyzed sugar esters incorporating systematic mapping principles

Author(s)

Goncalves, Maria Carolina Pereira ^[1] ; Romanelli, Joao Paulo ^[2] ; Guimaraes, Jose Renato ^[1] ; Vieira, Ana Carolina ^[1] ; de Azevedo, Bruna Pereira ^[2] ; Tardioli, Paulo Waldir ^[1]

Affiliation

^[1] Fed Univ Sao Carlos UFSCar, Chem Engn Dept, Sao Carlos, SP - Brazil

^[2] Univ Sao Paulo, Dept Forest Sci, Luiz de Queiroz Coll Agr, Lab Ecol & Forest Restorat LERF, Piracicaba - Brazil

• Document type: Review article
• Source: CRITICAL REVIEWS IN BIOTECHNOLOGY; v. 41, n. 6, p. 865-878, AUG 18 2021.
• Web of Science Citations: 3

Abstract

Rigorous evidence reviews must follow specific guidelines designed to improve transparency, reproducibility, and to minimize biases to which traditional reviews are susceptible. While evidence synthesis methods, such as systematic reviews and maps, have been used in several research fields, the majority of reviews published in the realm of chemical engineering are nonsystematic. In this study, we incorporated principles of systematic mapping to conduct a literature review covering research on the synthesis of sugar fatty acid esters (SFAE) with Candida antarctica lipase B (CALB). Our results showed that the simple monosaccharides were the most cited sugars among studies we conducted. The direct use of renewable raw materials and frequently available resources to produce alternative sugar esters (SE) was scarcely reported in our data set. We found that free fatty acids (FFA) were the most commonly cited acyl donors amongst all publications, with lauric, oleic, and palmitic acids accounting for similar to 43% of the occurrences. Tertiary alcohols (ter-butyl alcohol (T-but) and 2-methyl-2-butanol (2M2B)) and ionic liquids were the most used solvents to synthesize SE. The co-occurence analysis of keywords involving solvent terms showed that most of the papers evaluated different solvents as reaction media (mostly in the form of a bisolvent system), also investigating the impact of their choice on sugar ester productivities. Given the potential of reviews informing us of research decisions, this article reveals trends and spaces across CALB-catalyzed SE synthesis research, in addition to introducing a new methodological perspective for developing reviews in the field of chemical engineering. (AU)

• FAPESP's process: 19/08533-4 - Understanding ecological and social aspects of restoration actions in tropical regions through systematic reviews and meta-analyses
• Grantee: João Paulo Romanelli
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/23908-4 - Design of new biocatalizers by surface modifications of post-immobilization lipases for application in xylose oleate synthesis
• Grantee: Maria Carolina Pereira Gonçalves
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 16/10636-8 - From the cell factory to the Biodiesel-Bioethanol integrated biorefinery: a systems approach applied to complex problems in micro and macroscales
• Grantee: Roberto de Campos Giordano
• Support Opportunities: Program for Research on Bioenergy (BIOEN) - Thematic Grants