A portable system for photoelectrochemical detection of lactate on TiO2 nanoparticles and [Ni(salen)] polymeric film

Author(s)

Bott-Neto, Jose L. ^[1] ; Martins, Thiago S. ^[2] ; Buscaglia, Lorenzo A. ^[1] ; Santiago, Patricia V. B. ^[3] ; Fernandez, Pablo S. ^[3] ; Machado, Sergio A. S. ^[2] ; Oliveira Jr, Osvaldo N.

Affiliation

^[1] Univ Sao Paulo, Sao Carlos Inst Phys, BR-13560970 Sao Carlos, SP - Brazil

^[2] Univ Sao Paulo, Sao Carlos Inst Chem, BR-13560970 Sao Carlos, SP - Brazil

^[3] Univ Estadual Campinas, Inst Chem, BR-13083970 Campinas, SP - Brazil

• Document type: Journal article
• Source: SENSORS AND ACTUATORS B-CHEMICAL; v. 345, OCT 15 2021.
• Web of Science Citations: 0

Abstract

In this paper we present a portable photoelectrochemical system developed with screen-printed carbon electrodes (SPCEs) and a 3 W light-emitting diode (LED). The device with 3D printed structure was applied for detecting lactate on TiO2 nanoparticles modified with {[}Ni(salen)] polymer film (referred to as TiO2@poly{[}Ni (salen)]). Electrode coating with the polymer increased the sensitivity of the photoelectrochemical sensor, resulting in a linear range from 0.1 to 20 mmol L-1 with a limit of detection (LOD) of 88 mu mol L-1. The sensing system exhibited excellent stability, reproducibility, and selectivity. We also demonstrated by in situ Fouriertransform infrared spectroscopy (FTIR) measurements that carbon dioxide (CO2) is the main product from photoelectrooxidation of lactate on TiO2@poly{[}Ni(salen)]. The portable system can be employed with any type of modified electrodes to function as photoelectroanalytical (bio)sensors, especially for point-of-care diagnostics. (AU)

• FAPESP's process: 18/22214-6 - Toward a convergence of technologies: from sensing and biosensing to information visualization and machine learning for data analysis in clinical diagnosis
• Grantee: Osvaldo Novais de Oliveira Junior
• Support type: Research Projects - Thematic Grants
• FAPESP's process: 19/00101-8 - Development of a portable impedance analyzer
• Grantee: Lorenzo Antonio Buscaglia
• Support type: Scholarships in Brazil - Master
• FAPESP's process: 17/11986-5 - Research Division 1 - dense energy carriers
• Grantee: Ana Flávia Nogueira
• Support type: Research Grants - Research Centers in Engineering Program
• FAPESP's process: 19/13514-9 - Electrochemical sensors with a matrix containing graphene quantum dots or nanoribbons for the detection of biomarkers
• Grantee: José Luiz Bott Neto
• Support type: Scholarships in Brazil - Post-Doctorate
• FAPESP's process: 18/20952-0 - Applied and fundamental studies of the electrochemical conversion of alcohols and CO2
• Grantee: Pablo Sebastián Fernández
• Support type: Program for Research on Bioenergy (BIOEN) - Regular Program Grants