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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Greener organic synthetic methods: Sonochemistry and heterogeneous catalysis promoted multicomponent reactions

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Author(s):
V. Machado, Ingrid [1] ; Santos, Jhonathan R. N. dos [1] ; Januario, Marcelo A. P. [1] ; Correa, Arlene G. [1]
Total Authors: 4
Affiliation:
[1] Univ Fed Sao Carlos, Dept Chem, Ctr Excellence Res Sustainable Chem, BR-13565905 Sao Carlos, SP - Brazil
Total Affiliations: 1
Document type: Review article
Source: ULTRASONICS SONOCHEMISTRY; v. 78, OCT 2021.
Web of Science Citations: 0
Abstract

Ultrasound is an essential technique to improve organic synthesis from the point of view of green chemistry, as it can promote better yields and selectivities, in addition to shorter reaction times when compared to the conventional methods. Heterogeneous catalysis is another pillar of sustainable chemistry being the recycling and reuse of the catalysts one of its great advantage. In the other hand, multicomponent reactions provide the synthesis of structurally diverse compounds, in a one-pot fashion, without isolation and purification of intermediates. Thus, the combination of these protocols has proved to be a powerful tool to obtain biologically active organic compounds with lower costs, time and energy consumption. Herein, we provide a comprehensive overview of advances on methods of organic synthesis that have been reported over the past ten years with focus on ultrasound-assisted multicomponent reactions under heterogeneous catalysis. In particular, we present pharmacologically important N- and O-heterocyclic compounds, considering their synthetic methods using green solvents, and catalyst recycling. (AU)

FAPESP's process: 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery
Grantee:Glaucius Oliva
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock
Grantee:Arlene Gonçalves Corrêa
Support Opportunities: Research Grants - Research Centers in Engineering Program