n eco-friendly approach for the recovery of astaxanthin and 8-carotene from Phaffia rhodozyma biomass using bio-based solvent

Author(s)

Mussagy, Cassamo U. ^{[1, 2]} ; Kurnia, Kiki A. ^[3] ; Dias, Ana C. R. V. ^[4] ; Raghavan, Vijaya ^[5] ; Santos-Ebinuma, Valeria C. ^[2] ; Pessoa Jr, Adalberto

Affiliation

^[1] Univ Sao Paulo, Sch Pharmaceut Sci, Dept Pharmaceut Biochem Technol, Sao Paulo - Brazil

^[2] Sao Paulo State Univ UNESP, Sch Pharmaceut Sci, Dept Engn Bioproc & Biotechnol, BR-14800903 Araraquara, SP - Brazil

^[3] Inst Teknol Bandung, Fac Ind Technol, Dept Chem Engn, Jalan Ganesha 10, Bandung 1040132 - Indonesia

^[4] Univ Aveiro, Dept Environm & Planning, CESAM Ctr Environm & Marine Studies, P-3810193 Aveiro - Portugal

^[5] McGill Univ, Fac Agr & Environm Sci, Dept Bioresource Engn, Montreal, PQ - Canada

• Document type: Journal article
• Source: Bioresource Technology; v. 345, FEB 2022.
• Web of Science Citations: 0

Abstract

There is a growing demand in the development of environmentally friendly technologies, based on the use of more biocompatible solvents for the recovery of natural bioactive compounds. In this work, the red yeast Phaffia rhodozyma biomass was used as a source of carotenoids to develop an integrative and efficient platform that promotes the recovery of astaxanthin and 8-carotene using bio-based solvents (BioSs). The extraction aptitude of pure BioSs was evaluated and compared with the conventional organic method. At this point, the influence of the BioSs molecular structures involved in the extraction procedures were also investigated. Overall, envisaging the industrial application of the process, an integrative platform was proposed for the recovery of astaxanthin/ 8-carotene from P. rhodozyma biomass and the recycle of the BioSs. The life cycle assessment of the proposed technology using EtOH was evaluated, validating the sustainability of BioSs in the process with environmental impact reduction of 3-12%. (AU)

• FAPESP's process: 20/08655-0 - Development of a sustainable and biocompatible technology for Astaxanthin recovery and purification: a powerful antioxidant with economic value
• Grantee: Cassamo Ussemane Mussagy
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/15493-9 - Development of ionic liquids-based electroconductive hydrogels
• Grantee: Valéria de Carvalho Santos Ebinuma
• Support Opportunities: Regular Research Grants
• FAPESP's process: 18/06908-8 - Development of sustainable nanomaterials for the purification of antileukemic drugs
• Grantee: Valéria de Carvalho Santos Ebinuma
• Support Opportunities: Regular Research Grants
• FAPESP's process: 21/06686-8 - Biotechnological process for the development of natural colorants from microbial sources for industrial application: phase II
• Grantee: Valéria de Carvalho Santos Ebinuma
• Support Opportunities: Program for Research on Bioenergy (BIOEN) - Young Investigators Grants - Phase 2