Opinion on the Hurdles and Potential Health Benefits in Value-Added Use of Plant Food Processing By-Products as Sources of Phenolic Compounds

Author(s)

de Camargo, Adriano Costa ; Schwember, Andres R. ; Parada, Roberto ; Garcia, Sandra ; Marostica Junior, Mario Roberto ; Franchin, Marcelo ; Bismara Regitano-d'Arce, Marisa Aparecida ; Shahidi, Fereidoon

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; v. 19, n. 11, p. 47-pg., 2018-11-01.

Abstract

Plant foods, their products and processing by-products are well recognized as important sources of phenolic compounds. Recent studies in this field have demonstrated that food processing by-products are often richer sources of bioactive compounds as compared with their original feedstock. However, their final application as a source of nutraceuticals and bioactives requires addressing certain hurdles and challenges. This review discusses recent knowledge advances in the use of plant food processing by-products as sources of phenolic compounds with special attention to the role of genetics on the distribution and biosynthesis of plant phenolics, as well as their profiling and screening, potential health benefits, and safety issues. The potentialities in health improvement from food phenolics in animal models and in humans is well substantiated, however, considering the emerging market of plant food by-products as potential sources of phenolic bioactives, more research in humans is deemed necessary. (AU)

• FAPESP's process: 15/50333-1 - COBRA: a novel compound discovery pipeline for rapid and cost-effective identification of bioactives with health beneficial effects in Brazilian crops
• Grantee: Glaucia Maria Pastore
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 16/15563-9 - Characterization of new pharmacological targets and study of the activity of a 4-phenyl coumarin in the differentiation of Th17 lymphocytes in the development of periodontal disease
• Grantee: Marcelo Franchin
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 12/17683-0 - GAMMA RADIATION AS A TOOL FOR AGRO-INDUSTRIAL WASTES MICROBIOLOGICAL SAFETY AND ITS EFFECT ON THE ANTIOXIDANT PROPERTIES EVALUATED BY IN VITRO TESTS AND MODEL SYSTEMS
• Grantee: Adriano Costa de Camargo
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 15/00336-4 - Enzyme assited extraction of insoluble-bound phenolics from grape by-products: antioxidant and bioactivity potential
• Grantee: Adriano Costa de Camargo
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate