COBRA: a novel compound discovery pipeline for rapid and cost-effective identification of bioactives with health beneficial effects in Brazilian crops

• Grant number: 15/50333-1
• Support type: Research Projects - Thematic Grants
• Duration: April 01, 2016 - July 31, 2021
• Field of knowledge: Agronomical Sciences - Food Science and Technology - Food Science
• Cooperation agreement: Innovation Fund Denmark
• Principal researcher: Glaucia Maria Pastore
• Grantee: Glaucia Maria Pastore
• Principal researcher abroad: Karsten Kristiansen
• Institution abroad: University of Copenhagen, Denmark
• Home Institution: Faculdade de Engenharia de Alimentos (FEA). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated scholarship(s): 19/12244-8 - Effect of jabuticaba (Plinia jaboticaba) peel supplementation on metabolic profile in obese pre-diabetic subjects: a randomized, double-blinded, controlled trial, BP.DR

Abstract

These project aims to catalogue these bioactive compounds through a combination of chemoinformatics analyses, comprehensive data mining, and de-novo discovery and structural characterization of novel compounds. A comprehensive digitalized library of compounds will increase the knowledge and potential use of Brazilian native crops for the development of novel supplements/food with documented beneficial health promoting properties. Both the database and chemoinformatics tool developed in the project will serve as a resource for both public and private research. Finally, the project is expected to result in at least one new product using ingredients from the studied Brazilian crops. (AU)

Scientific publications

(86)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LAIBER PASCOAL, GABRIELA DE FREITAS; DE ALMEIDA SOUSA CRUZ, MARTA ANGELA; DE ABREU, JOEL PIMENTEL; BARROS SANTOS, MILLENA CRISTINA; FANARO, GUSTAVO BERNARDES; MAROSTICA JUNIOR, MARIO ROBERTO; SILVA, OTNIEL FREITAS; ALVES MOREIRA, RICARDO FELIPE; CAMERON, LUIZ CLAUDIO; LARRAZ FERREIRA, MARIANA SIMOES; TEODORO, ANDERSON JUNGER. Evaluation of the antioxidant capacity, volatile composition and phenolic content of hybrid Vitis vinifera L. varieties sweet sapphire and sweet surprise. Food Chemistry, v. 366, JAN 1 2022. Web of Science Citations: 0.

VALLE, MARIA C. P. R.; VIEIRA, ISABEL A.; FINO, LUCIANA C.; GALLINA, DARLILA A.; ESTEVES, ANDREA M.; DA CUNHA, DIOGO T.; CABRAL, LUCELIA; BENATTI, FABIANA B.; MAROSTICA JUNIOR, MARIO R.; BATISTA, ANGELA G.; SANTOS, ROSANGELA; PASTORE, GLAUCIA M.; SARTORATTO, ADILSON; SIVIERI, KATIA; TIZIOTO, POLYANA C.; COUTINHO, LUIZ L.; ANTUNES, ADRIANE E. C. Immune status, well-being and gut microbiota in military supplemented with synbiotic ice cream and submitted to field training: a randomised clinical trial. BRITISH JOURNAL OF NUTRITION, v. 126, n. 12, p. 1794-1808, DEC 28 2021. Web of Science Citations: 0.

FARIAS, DAVID DE PAULO; DE ARAUJO, FABIO FERNANDES; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; CATHARINO, RODRIGO RAMOS; PASTORE, GLAUCIA MARIA. Effect of in vitro digestion on the bioaccessibility and bioactivity of phenolic compounds in fractions of Eugenia pyriformis fruit. Food Research International, v. 150, n. A DEC 2021. Web of Science Citations: 0.

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Underutilized plants of the Cactaceae family: Nutritional aspects and technological applications. Food Chemistry, v. 362, NOV 15 2021. Web of Science Citations: 0.

BARROS MARIUTTI, LILIAN REGINA; REBELO, KEMILLA SARMENTO; BISCONSIN-JUNIOR, ANTONIO; DE MORAIS, JANNE SANTOS; MAGNANI, MARCIANE; MALDONADE, IRIANI RODRIGUES; MADEIRA, NUNO RODRIGO; TIENGO, ANDREA; MAROSTICA, JR., MARIO ROBERTO; BETIM CAZARIN, CINTHIA BAU. The use of alternative food sources to improve health and guarantee access and food intake. Food Research International, v. 149, NOV 2021. Web of Science Citations: 0.

TARONE, ADRIANA GADIOLI; GOUPY, PASCALE; GINIES, CHRISTIAN; MAROSTICA JUNIOR, MARIO ROBERTO; DUFOUR, CLAIRE. Advanced characterization of polyphenols from Myrciaria jaboticaba peel and lipid protection in in vitro gastrointestinal digestion. Food Chemistry, v. 359, OCT 15 2021. Web of Science Citations: 0.

ARAUJO, NAYARA MACEDO PEIXOTO; SILVA, ERIC KEVEN; ARRUDA, HENRIQUE SILVANO; DE MORAIS, DAMILA RODRIGUES; MEIRELES, MARIA ANGELA A.; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA. Recovering phenolic compounds from Eugenia calycina Cambess employing high-intensity ultrasound treatments: A comparison among its leaves, fruit pulp, and seed as promising sources of bioactive compounds. Separation and Purification Technology, v. 272, OCT 1 2021. Web of Science Citations: 0.

APARECIDA PEREIRA, ANA PAULA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; DE SOUZA-SPORKENS, JANE CRISTINA; DA SILVA, TOMAZ ANTONIO; FRANCO DE OLIVEIRA, HELENA COUTINHO; PASTORE, GLAUCIA MARIA. Brazilian sunberry (Solanum oocarpum Sendtn): Alkaloid composition and improvement of mitochondrial functionality and insulin secretion of INS-1E cells. Food Research International, v. 148, OCT 2021. Web of Science Citations: 0.

DE OLIVEIRA, WILLIARA QUEIROZ; DE AZEREDO, HENRIETTE MONTEIRO CORDEIRO; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Food packaging wastes amid the COVID-19 pandemic: Trends and challenges. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 116, p. 1195-1199, OCT 2021. Web of Science Citations: 1.

PAULINO, BRUNO N.; MOLINA, GUSTAVO; PASTORE, GLAUCIA M.; BICAS, JULIANO L. Current perspectives in the biotechnological production of sweetening syrups and polyols. CURRENT OPINION IN FOOD SCIENCE, v. 41, p. 36-43, OCT 2021. Web of Science Citations: 0.

PAULINO, BRUNO N.; SALES, ADONES; FELIPE, LORENA DE OLIVEIRA; PASTORE, GLAUCIA M.; MOLINA, GUSTAVO; BICAS, JULIANO L. Biotechnological production of non-volatile flavor compounds. CURRENT OPINION IN FOOD SCIENCE, v. 41, p. 26-35, OCT 2021. Web of Science Citations: 0.

ARAUJO, NAYARA MACEDO PEIXOTO; ARRUDA, HENRIQUE SILVANO; MARQUES, DAVID ROGER PAIXAO; OLIVEIRA, WILLIARA QUEIROZ DE; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA. Functional and nutritional properties of selected Amazon fruits: A review. Food Research International, v. 147, SEP 2021. Web of Science Citations: 0.

REBELO, KEMILLA S.; CAZARIN, CINTHIA B. B.; IGLESIAS, AMADEU H.; STAHL, MARCELLA A.; KRISTIANSEN, KARSTEN; CARVALHO-ZILSE, GISLENE A.; GRIMALDI, RENATO; REYES, FELIX G. R.; DANNESKIOLD-SAMSOE, NIELS B.; JUNIOR, MARIO R. M. Nutritional composition and bioactive compounds of Melipona seminigra pot-pollen from Amazonas, Brazil. Journal of the Science of Food and Agriculture, v. 101, n. 12, p. 4907-4915, SEP 2021. Web of Science Citations: 0.

BASEGGIO, ANDRESSA MARA; KIDO, LARISSA AKEMI; VIGANO, JULIANE; CARNEIRO, MARA JUNQUEIRA; LAMAS, CELINA DE ALMEIDA; MARTINEZ, JULIAN; SAWAYA, ALEXANDRA CHRISTINE HELENA FRANKLAND; CAGNON, VALERIA HELENA ALVES; MAROSTICA JUNIOR, MARIO ROBERTO. Systemic antioxidant and anti-inflammatory effects of yellow passion fruit bagasse extract during prostate cancer progression. JOURNAL OF FOOD BIOCHEMISTRY, AUG 2021. Web of Science Citations: 0.

SANZANA, SIGRID; RODRIGUEZ, LYANNE; BARRAZA BARRIONUEVO, HAYLEEN; ALBORNOZ POBLETE, CESAR; MAROSTICA JUNIOR, MARIO ROBERTO; FUENTES, EDUARDO; PALOMO, IVAN. Antiplatelet Activity of Cucurbita maxima. JOURNAL OF MEDICINAL FOOD, AUG 2021. Web of Science Citations: 0.

RODRIGUES, ALEXSANDRA PEREIRA; PASTORE, GLAUCIA MARIA. A review of the nutritional composition and current applications of monguba (Pachira aquatica Aubl.) plant. Journal of Food Composition and Analysis, v. 99, JUN 2021. Web of Science Citations: 1.

ARRUDA, HENRIQUE SILVANO; SILVA, ERIC KEVEN; PEIXOTO ARAUJO, NAYARA MACEDO; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO. Anthocyanins Recovered from Agri-Food By-Products Using Innovative Processes: Trends, Challenges, and Perspectives for Their Application in Food Systems. Molecules, v. 26, n. 9 MAY 2021. Web of Science Citations: 1.

RODRIGUES, ALEXSANDRA PEREIRA; NATHIA-NEVES, GRAZIELLE; PEREIRA, GUSTAVO ARAUJO; MASSARIOLI, ADNA PRADO; DE ALMEIDA MEIRELES, MARIA ANGELA; DE ALENCAR, SEVERINO MATIAS; PASTORE, GLAUCIA MARIA. Obtaining high-quality oil from monguba (Pachira aquatica Aubl.) seeds by using supercritical CO2 process. JOURNAL OF SUPERCRITICAL FLUIDS, v. 171, MAY 2021. Web of Science Citations: 3.

DE SOUZA, FLORISVALDO GAMA; NATHIA-NEVES, GRAZIELLE; DE ARAUJO, FABIO FERNANDES; DIAS AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; NERI-NUMA, IRAMAIA ANGELICA; CATHARINO, RODRIGO RAMOS; DE ALENCAR, SEVERINO MATIAS; DE ALMEIDA MEIRELES, MARIA ANGELA; PASTORE, GLAUCIA MARIA. Evaluation of antioxidant capacity, fatty acid profile, and bioactive compounds from buritirana (Mauritiella armata Mart.) oil: A little-explored native Brazilian fruit. Food Research International, v. 142, APR 2021. Web of Science Citations: 0.

ARAUJO, NAYARA MACEDO PEIXOTO; ARRUDA, HENRIQUE SILVANO; FARIAS, DAVID DE PAULO; MOLINA, GUSTAVO; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA. Plants from the genus Eugenia as promising therapeutic agents for the management of diabetes mellitus: A review. Food Research International, v. 142, APR 2021. Web of Science Citations: 0.

GERALDI, MARINA VILAR; BETIM CAZARIN, CINTHIA BAU; DIAS-AUDIBERT, FLAVIA LUISA; PEREIRA, GUSTAVO ARAUJO; CARVALHO, GABRIELA GUIMARAES; KABUKI, DIRCE YORIKA; CATHARINO, RODRIGO RAMOS; PASTORE, GLAUCIA MARIA; BEHRENS, JORGE HERMAN; CRISTIANINI, MARCELO; MAROSTICA JUNIOR, MARIO ROBERTO. Influence of high isostatic pressure and thermal pasteurization on chemical composition, color, antioxidant properties and sensory evaluation of jabuticaba juice. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 139, MAR 2021. Web of Science Citations: 2.

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; DE SOUZA, FLORISVALDO GAMA; CATHARINO, RODRIGO RAMOS; DO SACRAMENTO, CELIO KERSUL; PASTORE, GLAUCIA MARIA. Influence of high-intensity ultrasound on color, chemical composition and antioxidant properties of araca-boi pulp. Food Chemistry, v. 338, FEB 15 2021. Web of Science Citations: 1.

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Polyphenols and their applications: An approach in food chemistry and innovation potential. Food Chemistry, v. 338, FEB 15 2021. Web of Science Citations: 0.

MACHADO, ANA PAULA DA FONSECA; GERALDI, MARINA VILAR; NASCIMENTO, ROBERTO DE PAULA DO; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; VEZZA, TERESA; DIEZ-ECHAVE, PATRICIA; JUAN GALVAZ, JULIO; CAZARIN, CINTHIA BAU BETIM; MAROSTICA JUNIOR, MARIO ROBERTO. Polyphenols from food by-products: An alternative or complementary therapy to IBD conventional treatments. Food Research International, v. 140, FEB 2021. Web of Science Citations: 2.

REBELO, KEMILLA S.; CAZARIN, CINTHIA B. B.; IGLESIAS, AMADEU H.; STAHL, MARCELLA A.; KRISTIANSEN, KARSTEN; CARVALHO-ZILSE, GISLENE A.; GRIMALDI, RENATO; REYES, FELIX G. R.; DANNESKIOLD-SAMSOE, NIELS B.; JUNIOR, MARIO R. M. Nutritional composition and bioactive compounds of Melipona seminigra pot-pollen from Amazonas, Brazil. Journal of the Science of Food and Agriculture, FEB 2021. Web of Science Citations: 0.

TARONE, ADRIANA GADIOLI; SILVA, ERIC KEVEN; BARROS, HELENA DIAS DE FREITAS QUEIROZ; CAZARIN, CINTHIA BAU BETIM; JUNIOR, MARIO ROBERTO MAROSTICA. High-intensity ultrasound-assisted recovery of anthocyanins from jabuticaba by-products using green solvents: Effects of ultrasound intensity and solvent composition on the extraction of phenolic compounds. Food Research International, v. 140, FEB 2021. Web of Science Citations: 6.

TARONE, ADRIANA GADIOLI; SILVA, ERIC KEVEN; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, JR., MARIO ROBERTO. Inulin/fructooligosaccharides/pectin-based structured systems: Promising encapsulating matrices of polyphenols recovered from jabuticaba peel. FOOD HYDROCOLLOIDS, v. 111, FEB 2021. Web of Science Citations: 4.

AGUIAR, LAIS MARINHO; BICAS, JULIANO LEMOS; FUENTES, EDUARDO; ALARCON, MARCELO; GONZALEZ, IVAN PALOMO; PASTORE, GLAUCIA MARIA; MAROSTICA JUNIOR, MARIO ROBERTO; CAZARIN, CINTHIA BAU BETIM. Non-nutrients and nutrients from Latin American fruits for the prevention of cardiovascular diseases. Food Research International, v. 139, JAN 2021. Web of Science Citations: 0.

APARECIDA PEREIRA, ANA PAULA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; ADANI, HELOISA BANIN; SOUZA USBERTI, FRANCIANE COLARES; PAULINO, BRUNO NICOLAU; PEDROSA SILVA CLERICI, MARIA TERESA; NERI-NUMA, IRAMAIA ANGELICA; ALVES MORO, THAISA DE MENEZES; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Impact of ripening on the health-promoting components from fruta-do-lobo (Solanum lycocarpum St. Hill). Food Research International, v. 139, JAN 2021. Web of Science Citations: 0.

DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; DE SOUZA, FLORISVALDO GAMA; CATHARINO, RODRIGO RAMOS; DO SACRAMENTO, CELIO KERSUL; PASTORE, GLAUCIA MARIA. Chemical characterization of Eugenia stipitata: A native fruit from the Amazon rich in nutrients and source of bioactive compounds. Food Research International, v. 139, JAN 2021. Web of Science Citations: 1.

DO NASCIMENTO, ROBERTO DE PAULA; MOYA, AMANDA MARIA TOMAZINI MUNHOZ; MACHADO, ANA PAULA DA FONSECA; GERALDI, MARINA VILAR; DIEZ-ECHAVE, PATRICIA; VEZZA, TERESA; GALVEZ, JULIO; CAZARIN, CINTHIA BAIL BETIM; MAROSTICA, JR., MARIO ROBERTO. Review on the potential application of non-phenolic compounds from native Latin American food byproducts in inflammatory bowel diseases. Food Research International, v. 139, JAN 2021. Web of Science Citations: 0.

FUENTES, EDUARDO; TROSTCHANSKY, ANDRES; REGUENGO, LIVIA M.; JUNIOR, MARIO R. M.; PALOMO, IVAN. Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace. CURRENT DRUG TARGETS, v. 22, n. 15, p. 1716-1724, 2021. Web of Science Citations: 0.

ALEXANDRINO, THAIS DOLFINI; TOMAZINI MUNHOZ MOYA, AMANDA MARIA; MADUREIRA DE MEDEIROS, TIAGO DANIEL; MORARI, JOSEANE; VELLOSO, LICIO AUGUSTO; LEAL, RAQUEL FRANCO; MAROSTICA, MARIO ROBERTO; PASTORE, GLAUCIA MARIA; BETIM CAZARIN, CINTHIA BAU; BICAS, JULIANO LEMOS. Anti-inflammatory effects of monoterpenoids in rats with TNBS-induced colitis. PHARMANUTRITION, v. 14, DEC 2020. Web of Science Citations: 0.

ARRUDA, HENRIQUE SILVANO; NERI-NUMA, IRAMAIA ANGELICA; KIDO, LARISSA AKEMI; MAROSTICA JUNIOR, MARIO ROBERTO; PASTORE, GLAUCIA MARIA. Recent advances and possibilities for the use of plant phenolic compounds to manage ageing-related diseases. Journal of Functional Foods, v. 75, DEC 2020. Web of Science Citations: 0.

DE SOUZA, FLORISVALDO GAMA; DE ARAUJO, FABIO FERNANDES; FARIAS, DAVID DE PAULO; ZANOTTO, ALINE WASEM; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Brazilian fruits of Arecaceae family: An overview of some representatives with promising food, therapeutic and industrial applications. Food Research International, v. 138, n. A DEC 2020. Web of Science Citations: 0.

FARIAS, DAVID DE PAULO; DE ARAUJO, FABIO FERNANDES; NERI-NUMA, IRAMAIA ANGELICA; DIAS-AUDIBERT, FLAVIA LUISA; DELAFIORI, JEANY; CATHARINO, RODRIGO RAMOS; PASTORE, GLAUCIA MARIA. Distribution of nutrients and functional potential in fractions of Eugenia pyriformis: An underutilized native Brazilian fruit. Food Research International, v. 137, NOV 2020. Web of Science Citations: 2.

PEIXOTO ARAUJO, NAYARA MACEDO; ARRUDA, HENRIQUE SILVANO; DOS SANTOS, FABIO NEVES; DE MORAIS, DAMILA RODRIGUES; PEREIRA, GUSTAVO ARAUJO; PASTORE, GLAUCIA MARIA. LC-MS/MS screening and identification of bioactive compounds in leaves, pulp and seed from Eugenia calycina Cambess. Food Research International, v. 137, NOV 2020. Web of Science Citations: 2.

BALLARD, CINTIA REIS; DOS SANTOS, ELISVANIA FREITAS; DUBOIS, MARIE-JULIE; PILON, GENEVIEVE; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO; MARETTE, ANDRE. Two polyphenol-rich Brazilian fruit extracts protect from diet-induced obesity and hepatic steatosis in mice. FOOD & FUNCTION, v. 11, n. 10, p. 8800-8810, OCT 1 2020. Web of Science Citations: 0.

NERI-NUMA, IRAMAIA ANGELICA; BETIM CAZARIN, CINTHIA BAU; TASCA GOIS RUIZ, ANA LUCIA; PAULINO, BRUNO NICOLAU; MOLINA, GUSTAVO; PASTORE, GLAUCIA MARIA. Targeting flavonoids on modulation of metabolic syndrome. Journal of Functional Foods, v. 73, OCT 2020. Web of Science Citations: 0.

SOUZA, ALANN THAFFARELL PORTILHO; FREITAS, GILEADE PEREIRA; LOPES, HELENA BACHA; TOTOLI, GABRIELA GUARALDO CAMPOS; TARONE, ADRIANA GADIOLI; MAROSTICA-JUNIOR, MARIO ROBERTO; ROSA, ADALBERTO LUIZ; BELOTI, MARCIO MATEUS. Jabuticaba peel extract modulates adipocyte and osteoblast differentiation of MSCs from healthy and osteoporotic rats. JOURNAL OF BONE AND MINERAL METABOLISM, v. 39, n. 2 SEP 2020. Web of Science Citations: 0.

NERI-NUMA, IRAMAIA ANGELICA; PESSOA, MARINA GABRIEL; ARRUDA, HENRIQUE SILVANO; PEREIRA, GUSTAVO ARAUJO; PAULINO, BRUNO NICOLAU; FIGUEIREDO ANGOLINI, CELIO FERNANDO; TASCA GOIS RUIZ, ANA LUCIA; PASTORE, GLAUCIA MARIA. Genipap (Genipa americana L.) fruit extract as a source of antioxidant and antiproliferative iridoids. Food Research International, v. 134, AUG 2020. Web of Science Citations: 0.

APARECIDA PEREIRA, ANA PAULA; CHATAGNIER LAURETTI, LEONARDO BORGES; ALVARENGA, VERONICA ORTIZ; PAULINO, BRUNO NICOLAU; FIGUEIREDO ANGOLINI, CELIO FERNANDO; NERI-NUMA, IRAMAIA ANGELICA; ORLANDO, EDUARDO ADILSON; LIMA PALLONE, JULIANA AZEVEDO; SANT'ANA, ANDERSON S.; PASTORE, GLAUCIA MARIA. Evaluation of fruta-do-lobo (Solanum lycocarpum St. Hill) starch on the growth of probiotic strains. Food Research International, v. 133, JUL 2020. Web of Science Citations: 0.

LOPES DO CARMO, MONICA CRISTINA; MARTINS, ISABELA MATEUS; MAGALHAES, ANA ELISA RAMOS; MAROSTICA JUNIOR, MARIO ROBERTO; MACEDO, JULIANA ALVES. Passion fruit (Passiflora edulis) leaf aqueous extract ameliorates intestinal epithelial barrier dysfunction and reverts inflammatory parameters in Caco-2 cells monolayer. Food Research International, v. 133, JUL 2020. Web of Science Citations: 0.

PRADO, LIVIA GARCIA; ARRUDA, HENRIQUE SILVANO; PEIXOTO ARAUJO, NAYARA MACEDO; DE OLIVEIRA BRAGA, LUCIA ELAINE; BANZATO, THAIS PETROCHELLI; PEREIRA, GUSTAVO ARAUJO; FIGUEIREDO, MARIANA CECCHETTO; TASCA GOIS RUIZ, ANA LUCIA; EBERLIN, MARCOS NOGUEIRA; DE CARVALHO, JOAO ERNESTO; VENDRAMINI-COSTA, DEBORA BARBOSA; PASTORE, GLAUCIA MARIA. Antioxidant, antiproliferative and healing properties of araticum (Annona crassiflora Mart.) peel and seed. Food Research International, v. 133, JUL 2020. Web of Science Citations: 0.

TARONE, ADRIANA GADIOLI; BETIM CAZARIN, CINTHIA BAU; MAROSTICA JUNIOR, MARIO ROBERTO. Anthocyanins: New techniques and challenges in microencapsulation. Food Research International, v. 133, JUL 2020. Web of Science Citations: 1.

KIDO, LARISSA AKEMI; HAHM, EUN-RYEONG; KIM, SU-HYEONG; BASEGGIO, ANDRESSA MARA; CAGNON, VALERIA HELENA ALVES; SINGH, SHIVENDRA V.; MAROSTICA, JR., MARIO ROBERTO. Prevention of Prostate Cancer in Transgenic Adenocarcinoma of the Mouse Prostate Mice by Yellow Passion Fruit Extract and Antiproliferative Effects of Its Bioactive Compound Piceatannol. JOURNAL OF CANCER PREVENTION, v. 25, n. 2, p. 87-99, JUN 2020. Web of Science Citations: 3.

NERI-NUMA, IRAMAIA ANGELICA; ARRUDA, HENRIQUE SILVANO; GERALDI, MARINA VILAR; MAROSTICA JUNIOR, MARIO ROBERTO; PASTORE, GLAUCIA MARIA. Natural prebiotic carbohydrates, carotenoids and flavonoids as ingredients in food systems. CURRENT OPINION IN FOOD SCIENCE, v. 33, p. 98-107, JUN 2020. Web of Science Citations: 7.

PASTORE, GLAUCIA MARIA. Inulin thermal stability in prebiotic carbohydrate-enriched araticum whey beverage. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 128, JUN 2020. Web of Science Citations: 3.

LAMAS, CELINA A.; KIDO, LARISSA A.; HERMES, TULIO A.; NOGUEIRA-LIMA, ELLEN; MINATEL, ELAINE; COLLARES-BUZATO, CARLA B.; MAROSTICA JR, MARIO R.; CAGNON, VALERIA H. A. Brazilian berry extract (Myrciaria jaboticaba): A promising therapy to minimize prostatic inflammation and oxidative stress. PROSTATE, v. 80, n. 11 MAY 2020. Web of Science Citations: 0.

NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Novel insights into prebiotic properties on human health: A review. Food Research International, v. 131, MAY 2020. Web of Science Citations: 0.

PEREIRA, GUSTAVO ARAUJO; ARRUDA, HENRIQUE SILVANO; DE MORAIS, DAMILA RODRIGUES; PEIXOTO ARAUJO, NAYARA MACEDO; PASTORE, GLAUCIA MARIA. Mutamba (Guazuma ulmifolia Lam.) fruit as a novel source of dietary fibre and phenolic compounds. Food Chemistry, v. 310, APR 25 2020. Web of Science Citations: 0.

MARSON, GABRIELA VOLLET; SOARES DE CASTRO, RUANN JANSER; DA COSTA MACHADO, MARIANA TEIXEIRA; ZANDONADI, FLAVIA DA SILVA; DE FREITAS QUEIROZ BARROS, HELENA DIAS; MAROSTICA JUNIOR, MARIO ROBERTO; SUSSULINI, ALESSANDRA; HUBINGER, MIRIAM DUPAS. Proteolytic enzymes positively modulated the physicochemical and antioxidant properties of spent yeast protein hydrolysates. Process Biochemistry, v. 91, p. 34-45, APR 2020. Web of Science Citations: 7.

VUOLO, MILENA MORANDI; LIMA, GLAUCIA CARIELO; BATISTA, ANGELA GIOVANA; BETIM CARAZIN, CINTHIA BAU; CINTRA, DENNYS ESPER; PRADO, MARCELO ALEXANDRE; MAROSTICA JUNIOR, MARIO ROBERTO. Passion fruit peel intake decreases inflammatory response and reverts lipid peroxidation and adiposity in diet-induced obese rats. Nutrition Research, v. 76, p. 106-117, APR 2020. Web of Science Citations: 0.

FARIAS, DAVID DE PAULO; NERI-NUMA, IRAMAIA ANGELICA; DE ARAUJO, FABIO FERNANDES; PASTORE, GLAUCIA MARIA. A critical review of some fruit trees from the Myrtaceae family as promising sources for food applications with functional claims. Food Chemistry, v. 306, FEB 15 2020. Web of Science Citations: 21.

LAMAS, C. A.; KIDO, L. A.; MONTICO, F.; COLLARES-BUZATO, C. B.; MAROSTICA, JR., M. R.; CAGNON, V. H. A. A jaboticaba extract prevents prostatic damage associated with aging and high-fat diet intake. FOOD & FUNCTION, v. 11, n. 2, p. 1547-1559, FEB 1 2020. Web of Science Citations: 1.

BATISTA, ANGELA GIOVANA; MENDONCA, MONIQUE CULTURATO P.; SOARES, EDILENE SIQUEIRA; DA SILVA-MAIA, JULIANA KELLY; DIONISIO, ANA PAULA; SARTORI, CESAR R.; DA CRUZ-HOFLING, MARIA ALICE; MAROSTICA JUNIOR, MARIO ROBERTO. Syzygium malaccense fruit supplementation protects mice brain against high-fat diet impairment and improves cognitive functions. Journal of Functional Foods, v. 65, FEB 2020. Web of Science Citations: 0.

QUATRIN, ANDREIA; RAMPELOTTO, CRISTINE; PAULETTO, ROBERSON; MAURER, LUANA HASELEIN; NICHELLE, SABRINA MARAFIGA; KLEIN, BRUNA; RODRIGUES, RENATA FRITZSCHE; MAROSTICA JUNIOR, MARIO ROBERTO; FONSECA, BRUNA DE SOUZA; DE MENEZES, CRISTIANO RAGAGNIN; MELLO, RENIUS DE OLIVEIRA; RODRIGUES, ELISEU; BOCHI, VIVIAN CAETANO; EMANUELLI, TATIANA. Bioaccessibility and catabolism of phenolic compounds from jaboticaba (Myrciaria trunciflora) fruit peel during in vitro gastrointestinal digestion and colonic fermentation. Journal of Functional Foods, v. 65, FEB 2020. Web of Science Citations: 0.

MAURER, LUANA HASELEIN; BETIM CAZARIN, CINTHIA BAU; QUATRIN, ANDREIA; NICHELLE, SABRINA MARAFIGA; MINUZZI, NATALIA MACHADO; TEIXEIRA, CIBELE FERREIRA; MANICA DA CRUZ, IVANA BEATRICE; MAROSTICA JUNIOR, MARIO ROBERTO; EMANUELLI, TATIANA. Dietary fiber and fiber-bound polyphenols of grape peel powder promote GSH recycling and prevent apoptosis in the colon of rats with TNBS-induced colitis. Journal of Functional Foods, v. 64, JAN 2020. Web of Science Citations: 0.

NERI-NUMA, IRAMAIA ANGELICA; DELLATORRE, ADRIANA; ORIANI, VIVIAN BOESSO; FRANCH, JR., GILBERTO CARLOS; FIGUEIREDO ANGOLINI, CELIO FERNANDO; HUBINGER, MIRIAM DUPAS; TASCA GOIS RUIZ, ANA LUCIA; PASTORE, GLAUCIA MARIA. In vitro bioactivity approach of unripe genipap (Genipa americana L., Rubiaceae) fruit extract and its solid lipid microparticle. Food Research International, v. 127, JAN 2020. Web of Science Citations: 0.

PEREIRA, GUSTAVO ARAUJO; SILVA, ERIC KEVEN; PEIXOTO ARAUJO, NAYARA MACEDO; ARRUDA, HENRIQUE SILVANO; MEIRELES, M. ANGELA A.; PASTORE, GLAUCIA MARIA. Mutamba seed mucilage as a novel emulsifier: Stabilization mechanisms, kinetic stability and volatile compounds retention. FOOD HYDROCOLLOIDS, v. 97, DEC 2019. Web of Science Citations: 1.

PEREIRA, GUSTAVO ARAUJO; PEIXOTO ARAUJO, NAYARA MACEDO; ARRUDA, HENRIQUE SILVANO; FARIAS, DAVID DE PAULO; MOLINA, GUSTAVO; PASTORE, GLAUCIA MARIA. Phytochemicals and biological activities of mutamba (Guazuma ulmifolia Lain.): A review. Food Research International, v. 126, DEC 2019. Web of Science Citations: 1.

FARIAS, DAVID DE PAULO; DE ARAUJO, FABIO FERNANDES; NERI-NUMA, IRAMAIA ANGELICA; PASTORE, GLAUCIA MARIA. Prebiotics: Trends in food, health and technological applications. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 93, p. 23-35, NOV 2019. Web of Science Citations: 0.

APARECIDA PEREIRA, ANA PAULA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; PAULINO, BRUNO NICOLAU; CHATAGNIER LAURETTI, LEONARDO BORGES; ORLANDO, EDUARDO ADILSON; SIQUEIRA SILVA, JOYCE GRAZIELLE; NERI-NUMA, IRAMAIA ANGELICA; REIS PIMENTEL SOUZA, JANE DELANE; LIMA PALLONE, JULIANA AZEVEDO; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. A comprehensive characterization of Solanum lycocarpum St. Hill and Solanum oocarpum Sendtn: Chemical composition and antioxidant properties. Food Research International, v. 124, n. SI, p. 61-69, OCT 2019. Web of Science Citations: 0.

BARROS HELENA, D. F. Q.; BASEGGIO ANDRESSA, M.; ANGOLINI CELIO, F. F.; PASTORE GLAUCIA, M.; CAZARIN CINTHIA, B. B.; MAROSTICA-JUNIOR MARIO, R. Influence of different types of acids and pH in the recovery of bioactive compounds in Jabuticaba peel (Plinia cauliflora). Food Research International, v. 124, n. SI, p. 16-26, OCT 2019. Web of Science Citations: 0.

VUOLO, MILENA MORANDI; BATISTA, ANGELA GIOVANA; TELLES BIASOTO, ALINE CAMARAO; CORREA, LUIZ CLAUDIO; MAROSTICA JUNIOR, MARIO ROBERTO; LIU, RUI HAI. Red-jambo peel extract shows antiproliferative activity against HepG2 human hepatoma cells. Food Research International, v. 124, n. SI, p. 93-100, OCT 2019. Web of Science Citations: 1.

ARRUDA, HENRIQUE SILVANO; PASTORE, GLAUCIA MARIA. Araticum (Annona crassiflora Mart.) as a source of nutrients and bioactive compounds for food and non-food purposes: A comprehensive review. Food Research International, v. 123, p. 450-480, SEP 2019. Web of Science Citations: 0.

DE ARAUJO, FABIO FERNANDES; NERI-NUMA, IRAMAIA ANGELICA; FARIAS, DAVID DE PAULO; MIRANDA CASTRO DA CUNHA, GABRYELLE RAHYARA; PASTORE, GLAUCIA MARIA. Wild Brazilian species of Eugenia genera (Myrtaceae) as an innovation hotspot for food and pharmacological purposes. Food Research International, v. 121, p. 57-72, JUL 2019. Web of Science Citations: 1.

PEREIRA, GUSTAVO ARAUJO; SILVA, ERIC KEVEN; PEIXOTO ARAUJO, NAYARA MACEDO; ARRUDA, HENRIQUE SILVANO; MEIRELES, M. ANGELA A.; PASTORE, GLAUCIA MARIA. Obtaining a novel mucilage from mutamba seeds exploring different high - intensity ultrasound process conditions. ULTRASONICS SONOCHEMISTRY, v. 55, p. 332-340, JUL 2019. Web of Science Citations: 6.

RODRIGUES, ALEXSANDRA PEREIRA; PEREIRA, GUSTAVO ARAUJO; FERREIRA TOME, PEDRO HENRIQUE; ARRUDA, HENRIQUE SILVANO; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Chemical Composition and Antioxidant Activity of Monguba (Pachira aquatica) Seeds. Food Research International, v. 121, p. 880-887, JUL 2019. Web of Science Citations: 0.

MARQUES, LETICIA A.; CAZARIN, CINTHIA B. B.; BICAS, JULIANO; MAROSTICA JUNIOR, MARIO R.; CARRILHO, EMANUEL; BOGUSZ JUNIOR, STANISLAU. Determination of Short Chain Fatty Acids in Mice Feces by Capillary Electrophoresis. Journal of the Brazilian Chemical Society, v. 30, n. 6, p. 1326-1333, JUN 2019. Web of Science Citations: 0.

DOS SANTOS, NATHALIA MEDINA; BATISTA, PATRICIA BERILLI; BATISTA, ANGELA GIOVANA; MAROSTICA JUNIOR, MARIO ROBERTO. Current evidence on cognitive improvement and neuroprotection promoted by anthocyanins. CURRENT OPINION IN FOOD SCIENCE, v. 26, n. SI, p. 71-78, APR 2019. Web of Science Citations: 1.

PEIXOTO ARAUJO, NAYARA MACEDO; PEREIRA, GUSTAVO ARAUJO; ARRUDA, HENRIQUE SILVANO; PRADO, LIVIA GARCIA; TASCA GOIS RUIZ, ANA LUCIA; EBERLIN, MARCOS NOGUEIRA; SOARES DE CASTRO, RUANN JANSER; PASTORE, GLAUCIA MARIA. Enzymatic treatment improves the antioxidant and antiproliferative activities of Adenanthera pavonina L. seeds. BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY, v. 18, MAR 2019. Web of Science Citations: 1.

DA SILVA-MAIA, JULIANA KELLY; BATISTA, ANGELA GIOVANA; CORREA, LUIZ CLAUDIO; LIMA, GLAUCIA CARIELO; BOGUSZ JUNIOR, STANISLAU; MAROSTICA JUNIOR, MARIO ROBERTO. Aqueous extract of berry (Plinia jaboticaba) byproduct modulates gut microbiota and maintains the balance on antioxidant defense system in rats. JOURNAL OF FOOD BIOCHEMISTRY, v. 43, n. 2 FEB 2019. Web of Science Citations: 3.

ARRUDA, HENRIQUE S.; SILVA, ERIC KEVEN; PEREIRA, GUSTAVO A.; ANGOLINI, CELIO FERNANDO F.; EBERLIN, MARCOS N.; MEIRELES, M. ANGELA A.; PASTORE, GLAUCIA M. Effects of high-intensity ultrasound process parameters on the phenolic compounds recovery from araticum peel. ULTRASONICS SONOCHEMISTRY, v. 50, p. 82-95, JAN 2019. Web of Science Citations: 7.

BALLARD, CINTIA R.; GALVAO, TAIS F.; CAZARIN, CINTHIA B. B.; MAROSTICA JR, MARIO R. Effects of Polyphenol-Rich Fruit Extracts on Diet-Induced Obesity in Rodents: Systematic Review and Meta-Analysis. CURRENT PHARMACEUTICAL DESIGN, v. 25, n. 32, p. 3484-3497, 2019. Web of Science Citations: 1.

DE CAMARGO, ADRIANO COSTA; SCHWEMBER, ANDRES R.; PARADA, ROBERTO; GARCIA, SANDRA; MAROSTICA JUNIOR, MARIO ROBERTO; FRANCHIN, MARCELO; BISMARA REGITANO-D'ARCE, MARISA APARECIDA; SHAHIDI, FEREIDOON. Opinion on the Hurdles and Potential Health Benefits in Value-Added Use of Plant Food Processing By-Products as Sources of Phenolic Compounds. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 19, n. 11 NOV 2018. Web of Science Citations: 7.

NERI-NUMA, IRAMAIA ANGELICA; FIGUEIREDO ANGOLINI, CELIO FERNANDO; BICAS, JULIANO LEMOS; TASCA GOIS RUIZ, ANA LUCIA; PASTORE, GLAUCIA MARIA. Iridoid blue-based pigments of Genipa americana L. (Rubiaceae) extract: Influence of pH and temperature on color stability and antioxidant capacity during in vitro simulated digestion. Food Chemistry, v. 263, p. 300-306, OCT 15 2018. Web of Science Citations: 1.

BATISTA, ANGELA GIOVANA; DA SILVA-MAIA, JULIANA KELLY; MENDONCA, MONIQUE CULTURATO P.; SOARES, EDILENE SIQUEIRA; LIMA, GLAUCIA CARIELO; BOGUSZ JUNIOR, STANISLAU; DA CRUZ-HOFLING, MARIA ALICE; MAROSTICA JUNIOR, MARIO ROBERTO. Jaboticaba berry peel intake increases short chain fatty acids production and prevent hepatic steatosis in mice fed high-fat diet. Journal of Functional Foods, v. 48, p. 266-274, SEP 2018. Web of Science Citations: 5.

PEREIRA, GUSTAVO ARAUJO; ARRUDA, HENRIQUE SILVANO; DE MORAIS, DAMILA RODRIGUES; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Carbohydrates, volatile and phenolic compounds composition, and antioxidant activity of calabura (Muntingia calabura L.) fruit. Food Research International, v. 108, p. 264-273, JUN 2018. Web of Science Citations: 11.

ARRUDA, HENRIQUE SILVANO; PEREIRA, GUSTAVO ARAUJO; DE MORAIS, DAMILA RODRIGUES; EBERLIN, MARCOS NOGUEIRA; PASTORE, GLAUCIA MARIA. Determination of free, esterified, glycosylated and insoluble-bound phenolics composition in the edible part of araticum fruit (Annona crassiflora Mart.) and its by-products by HPLC-ESI-MS/MS. Food Chemistry, v. 245, p. 738-749, APR 15 2018. Web of Science Citations: 17.

NERI-NUMA, IRAMAIA ANGELICA; SORIANO SANCHO, RENATA A.; APARECIDA PEREIRA, ANA PAULA; PASTORE, GLAUCIA MARIA. Small Brazilian wild fruits: Nutrients, bioactive compounds, health-promotion properties and commercial interest. Food Research International, v. 103, p. 345-360, JAN 2018. Web of Science Citations: 11.

RODRIGUES MANO, MARIO CEZAR; NERI-NUMA, IRAMAIA ANGELICA; DA SILVA, JULIANA BUENO; PAULINO, BRUNO NICOLAU; PESSOA, MARINA GABRIEL; PASTORE, GLAUCIA MARIA. Oligosaccharide biotechnology: an approach of prebiotic revolution on the industry. Applied Microbiology and Biotechnology, v. 102, n. 1, p. 17-37, JAN 2018. Web of Science Citations: 33.

BALDINI, TATIANA FERRARI; NERI-NUMA, IRAMAIA ANGELICA; DO SACRAMENTO, CELIO KERSUL; SCHMIELE, MARCIO; ANDRE BOLINI, HELENA MARIA; PASTORE, GLAUCIA MARIA; BICAS, JULIANO LEMOS. Elaboration and Characterization of Apple Nectars Supplemented with Araca-boi (Eugenia stipitata Mac Vaugh-Myrtaceae). BEVERAGES, v. 3, n. 4 DEC 2017. Web of Science Citations: 1.

PAULINO, BRUNO N.; PESSOA, MARINA G.; MOLINA, GUSTAVO; KAUPERT NETO, ANTONIO A.; OLIVEIRA, JULIANA V. C.; MANO, MARIO C. R.; PASTORE, GLAUCIA M. Biotechnological production of value-added compounds by ustilaginomycetous yeasts. Applied Microbiology and Biotechnology, v. 101, n. 21, p. 7789-7809, NOV 2017. Web of Science Citations: 6.

BATISTA, ANGELA G.; SOARES, EDILENE S.; MENDONCA, MONIQUE C. P.; DA SILVA, JULIANA K.; DIONISIO, ANA PAULA; SARTORI, CESAR R.; DA CRUZ-HOFLING, MARIA ALICE; MAROSTICA JUNIOR, MARIO R. Jaboticaba berry peel intake prevents insulin-resistance-induced tau phosphorylation in mice. MOLECULAR NUTRITION & FOOD RESEARCH, v. 61, n. 10 OCT 2017. Web of Science Citations: 13.

NERI-NUMA, IRAMAIA ANGELICA; PESSOA, MARINA GABRIEL; PAULINO, BRUNO NICOLAU; PASTORE, GLAUCIA MARIA. Genipin: A natural blue pigment for food and health purposes. TRENDS IN FOOD SCIENCE & TECHNOLOGY, v. 67, p. 271-279, SEP 2017. Web of Science Citations: 11.