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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Effect of ethylcellulose coating of albendazole-medicated feed on the efficacy of acanthocephalosis treatment in naturally parasitized tambaqui (Colossoma macropomum)

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Author(s):
Rafaelle P. CORDEIRO [1] ; Patrícia A. de C. BRAGA [2] ; Claudio M. JONSSON [3] ; Franmir R. BRANDÃO [4] ; Edsandra C. CHAGAS [5] ; Felix G. R. REYES [6]
Total Authors: 6
Affiliation:
[1] Universidade Estadual de Campinas - UNICAMP. School of Food Engineering. Department of Food Science and Nutrition - Brasil
[2] Universidade Estadual de Campinas - UNICAMP. School of Food Engineering. Department of Food Science and Nutrition - Brasil
[3] Embrapa Meio Ambiente - Brasil
[4] Embrapa Amazônia Ocidental - Brasil
[5] Embrapa Amazônia Ocidental - Brasil
[6] Universidade Estadual de Campinas - UNICAMP. School of Food Engineering. Department of Food Science and Nutrition - Brasil
Total Affiliations: 6
Document type: Journal article
Source: Acta Amazonica; v. 54, n. 2 2024-02-23.
Abstract

ABSTRACT Coating medicated fish feed with a polymer minimizes the chances of drug leaching into the water. Tambaqui (Colossoma macropomum) is an economically important Amazonian fish frequently parasitized by the acanthocephalan Neoechinorhynchus buttnerae. In this study, we compared the effect of ethylcellulose (EC 0.75%) coating of feed medicated with the antihelminthic albendazole (ABZ 10 mg kg bw-1) and uncoated feed on treatment efficacy and bioaccumulation of ABZ in naturally parasitized tambaqui during 35 days. Treatment efficacy was 34% and 66% in fish fed uncoated and coated feed, respectively, but did not vary significantly among treatments. Total ABZ residue reached concentrations from 122.0 to 151.7 ng g-1, and did not vary significantly among treatments. The biomagnification factor was low, ranging from 0.0003 to 0.0004. EC coating did not significantly affect the efficacy of ABZ treatment and did not interfere with ABZ bioaccumulation in the edible tissue of tambaqui. (AU)

FAPESP's process: 13/50452-5 - Veterinary drugs: development and validation of bioanalytical methods using LC-MS/MS and MALDI-TOF-MS and its applications in sanitary surveillance and the development of fish farming in Brazil
Grantee:Felix Guillermo Reyes Reyes
Support Opportunities: Research Grants - Research Partnership for Technological Innovation - PITE