Printed strips coated with a reticular organic framework for Non-Enzymatic detection of pesticides in the urine of rural workers

Author(s)

Martins, Thiago S. ; Henrique, Fabio J. F. S. ; Birolli, Willian G. ; Bott-Neto, Jose L. ; Silveira, Henrique C. S. ; Esteves, Pierre M. ; Oliveira Jr, Osvaldo N.

• Document type: Journal article
• Source: CHEMICAL ENGINEERING JOURNAL; v. 496, p. 9-pg., 2024-07-17.

Abstract

Monitoring the exposure of rural workers to pesticides during spraying is essential to safeguard their health, and this should ideally be done on the farms. In this work, we developed sensor strips coated with a reticular covalent organic framework (COF) which can detect paraquat and carbendazim simultaneously in artificial and human urine. Using electrochemical methods, a selective detection can be made of paraquat and carbendazim across concentrations ranging from 0.05 to 10 mu M, with detection limits of 0.01 and 0.05 mu M, respectively. This performance and selectivity may be attributed to a combination of high surface area, chemical composition and pore size of the COF used. Tests with undiluted urine samples were positive for at least one pesticide for all the nine rural workers taking part in the study. This highlights the need for monitoring pesticide levels, that can be done with the sensors presented here as they may be used with portable instruments with no sample pre-treatment. (AU)

• FAPESP's process: 22/03758-0 - Integrated dual electrochemical device for multiplexed detection of biomarkers
• Grantee: Thiago Serafim Martins
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 19/13514-9 - Electrochemical sensors with a matrix containing graphene quantum dots or nanoribbons for the detection of biomarkers
• Grantee: Jose Luiz Bott Neto
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 22/15122-3 - Developing new breathable tattoo (bio)sensors for health monitoring
• Grantee: Thiago Serafim Martins
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 18/22214-6 - Towards a convergence of technologies: from sensing and biosensing to information visualization and machine learning for data analysis in clinical diagnosis
• Grantee: Osvaldo Novais de Oliveira Junior
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 22/00243-0 - Developing new components and processes in visible light activated biosensors
• Grantee: Jose Luiz Bott Neto
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor