Semaglutide as a possible therapy for healthy aging: Targeting the hallmarks of aging

Author(s)

Ortiz, Gabriela Ueta ; de Freitas, Ellen Cristini

• Document type: Journal article
• Source: AGEING RESEARCH REVIEWS; v. 102, p. 4-pg., 2024-12-01.

Abstract

With an aging population, the investigation of therapies that promote healthy aging becomes increasingly urgent. Here we discuss how Semaglutide can be a potential therapy to contribute to this goal by targeting key hallmarks of aging, such as inflammation, oxidative stress and stem cell exhaustion. (AU)

• FAPESP's process: 22/00221-6 - Taurine supplementation associated or not with physical exercise: effect on the browning of white adipose tissue in elderly women with Sarcopenic Obesity
• Grantee: Gabriela Ueta Ortiz
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 22/15078-4 - Taurine supplementation associated or not with multicomponent training: effect on white adipose tissue browning and metabolic and molecular responses using the metabolomics approach in elderly women with Sarcopenic Obesity
• Grantee: Ellen Cristini de Freitas
• Support Opportunities: Regular Research Grants
• FAPESP's process: 19/11820-5 - Nr1d1 function on the aging-associated Sarcopenia
• Grantee: Adelino Sanchez Ramos da Silva
• Support Opportunities: Research Projects - Thematic Grants