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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Galleria mellonella as a model host for human pathogens

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Author(s):
Junqueira, Juliana Campos [1]
Total Authors: 1
Affiliation:
[1] Univ Estadual Paulista UNESP, Sao Jose dos Campos Dent Sch, Dept Biosci & Oral Diag, Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: VIRULENCE; v. 3, n. 6, p. 474-476, OCT 2012.
Web of Science Citations: 40
Abstract

The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. (AU)

FAPESP's process: 12/02184-9 - Interactions between different Candida species in experimental candidiasis of invertebrates and vertebrates models
Grantee:Juliana Campos Junqueira
Support Opportunities: Regular Research Grants