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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Whey protein hydrolysate enhances the exercise-induced heat shock protein (HSP70) response in rats

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de Moura, Carolina Soares [1] ; Barboza Lollo, Pablo Christiano [1] ; Morato, Priscila Neder [1] ; Carneiro, Everardo Magalhaes [2] ; Amaya-Farfan, Jaime [1]
Total Authors: 5
[1] Univ Estadual Campinas, Fac Food Engn, Dept Food & Nutr, Sao Paulo - Brazil
[2] Univ Estadual Campinas, Inst Biol, Dept Physiol & Biophys, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Food Chemistry; v. 136, n. 3-4, p. 1350-1357, FEB 1 2013.
Web of Science Citations: 20

Whey protein has been suggested to be potential protective agent against various forms of stress. The heat shock protein HSP70 confers greater cellular tolerance against stressors. The present study evaluated the effects of whey protein intake on HSP70 expression. Forty-eight male Wistar rats were divided into sedentary and exercised groups, and each group was fed as a protein source casein (CAS), whey protein (WP) or whey protein hydrolysate (WPH) for 3 weeks. Exercise on a treadmill was used as the source of stress in the animals from the exercised group. The results showed a larger increase in HSP70 expression in the soleus, gastrocnemius and lung of the WPH-fed rats than WP or casein-fed rats. HSP70 expression in the sedentary rats was very low, independent of the diet or tissue. Protein carbonyls were lower in the group that consumed WPH. These data suggest that the consumption of WPH enhances HSP70 expression. (C) 2012 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 10/02419-0 - The effect of consumption of hydrolyzed milk serum on the energetic metabolism and redox state of exercising rats
Grantee:Jaime Amaya Farfan
Support type: Regular Research Grants
FAPESP's process: 11/13035-1 - The effect of consumption of milk protein serums on HSP biomarkers and biochemical parameters in rats
Grantee:Jaime Amaya Farfan
Support type: Regular Research Grants