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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Complete Nucleotide Sequences of Two bla(KPC-2)-Bearing IncN Plasmids Isolated from Sequence Type 442 Klebsiella pneumoniae Clinical Strains Four Years Apart

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Author(s):
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Perez-Chaparro, Paula Juliana [1, 2] ; Cerdeira, Louise Teixeira [1, 3] ; Queiroz, Maise Gomes [4] ; Silva de Lima, Clayton Pereira [1] ; Levy, Carlos Emilio [5] ; Pavez, Monica [6] ; Lincopan, Nilton [6, 7] ; Goncalves, Evonnildo Costa [1, 4] ; Mamizuka, Elsa Masae [6] ; Mello Sampaio, Jorge Luiz [6, 3] ; Teixeira Nunes, Marcio Roberto [1] ; McCulloch, John Anthony [6, 1, 4]
Total Authors: 12
Affiliation:
[1] Minist Saude, SVS, Inst Evandro Chagas, Ctr Inovacoes Tecnol, Ananindeua, Para - Brazil
[2] Univ Guarulhos, Ctr Posgrad & Pesquisa, Dept Periodontia, Sao Paulo - Brazil
[3] Grp Fleury, Sao Paulo - Brazil
[4] Fed Univ Para, Inst Ciencias Biol, Lab Tecnol Biomol, BR-66059 Belem, Para - Brazil
[5] Univ Estadual Campinas, Fac Ciencias Med, Dept Patol Clin, Campinas, SP - Brazil
[6] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Anal Clin & Toxicol, LMDIAS, Sao Paulo - Brazil
[7] Univ Sao Paulo, Inst Ciencias Biomed, Dept Microbiol, BR-05508 Sao Paulo - Brazil
Total Affiliations: 7
Document type: Journal article
Source: Antimicrobial Agents and Chemotherapy; v. 58, n. 5, p. 2958-2960, MAY 2014.
Web of Science Citations: 9
Abstract

We sequenced the oldest bla(KPC-2)-bearing plasmid isolated in Brazil and another plasmid also carried by a Klebsiella pneumoniae strain of sequence type 442 (ST442), isolated 52 months later. Both plasmids present an IncN backbone and few acquired regions. Because the 2005 plasmid presented deletions and a truncated gene within Tn4401b compared to the 2009 plasmid, we can thus infer that IncN bla(KPC-2)-bearing plasmids pFCF1305 and pFCF3SP had a common ancestor circulating in Brazil prior to May 2005. (AU)

FAPESP's process: 13/12107-4 - Study of the heterogeneous resistance to vancomycin in Staphylococcus aureus by comparative single-cell genomics of subpopulations in a single isolate
Grantee:John Anthony Mcculloch
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 12/20915-0 - Metagenomic analysis of periodontal subgingival microbiota in subjects with and without periodontal disease
Grantee:Paula Juliana Perez Chaparro
Support Opportunities: Scholarships in Brazil - Post-Doctoral