| Full text | |
| Author(s): |
Total Authors: 2
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| Affiliation: | [1] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | Tetrahedron; v. 70, n. 20, p. 3291-3296, MAY 20 2014. |
| Web of Science Citations: | 6 |
| Abstract | |
An expedited synthesis of the bioprotective agent JP4-039 is described from N-Boc-L-leucinal in 50% overall yield. The synthesis involves the use of an alpha,beta-unsaturated diazoketone as the key intermediate, followed by a photochemical Wolff rearrangement in the presence of 4-amino-TEMPO (4-AT). (C) 2013 Elsevier Ltd. All rights reserved. (AU) | |
| FAPESP's process: | 12/22274-2 - Study in the photochemical Wolff rearrangement from a,b-unsaturated diazoketones. Aplication in diversity synthesis of nitrogen and oxygen heterocycles |
| Grantee: | Barbara Bernardim de Souza |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 09/54040-8 - Acquisition of a high-resolution Orbitrap mass spectrometer for the discovery and structural analysis of biologically active compounds: applications in proteomics, biomarkers, synthesis, isolation, and characterization of natural products, studies of redox systems in food and enzymatic synthesis |
| Grantee: | Emanuel Carrilho |
| Support Opportunities: | Multi-user Equipment Program |
| FAPESP's process: | 12/04685-5 - New synthetic methodologies for the construction of pyrrolidine, piperidine and indolizidine systems |
| Grantee: | Antonio Carlos Bender Burtoloso |
| Support Opportunities: | Regular Research Grants |