| Full text | |
| Author(s): |
Ferreira, A. I. C.
[1]
;
Brandao De Mattos, C. C.
[1]
;
Frederico, F. B.
[2]
;
Meira, C. S.
[3]
;
Almeida, Jr., G. C.
[2]
;
Nakashima, F.
[1]
;
Bernardo, C. R.
[1]
;
Pereira-Chioccola, V. L.
[3]
;
De Mattos, L. C.
[1]
Total Authors: 9
|
| Affiliation: | [1] Fac Med Sao Jose do Rio Preto FAMERP, Dept Biol Mol, Lab Imunogenet, BR-15090000 Sao Jose Do Rio Preto, SP - Brazil
[2] Hosp Base HB FUNFARME, Fundacao Fac Reg Med, Outpatient Eye Clin, Sao Jose Do Rio Preto, SP - Brazil
[3] Adolfo Lutz Inst, Parasitol Lab, Sao Paulo - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | EPIDEMIOLOGY AND INFECTION; v. 142, n. 1, p. 142-148, JAN 2014. |
| Web of Science Citations: | 22 |
| Abstract | |
The aim of this study was to investigate risk factors for ocular toxoplasmosis (OT) in patients who received medical attention at a public health service. Three hundred and forty-nine consecutive patients, treated in the Outpatient Eye Clinic of Hospital de Base, SAo Jose do Rio Preto, SAo Paulo state, Brazil, were enrolled in this study. After an eye examination, enzyme-linked immunosorbent assay (ELISA) was used to determine anti-Toxoplasma gondii antibodies. The results showed that 255% of the patients were seronegative and 745% were seropositive for IgG anti-T. gondii antibodies; of these 273% had OT and 727% had other ocular diseases (OOD). The presence of cats or dogs {[}odds ratio (OR) 222, 95% confidence interval (CI) 124-398, P=0009] and consumption of raw or undercooked meat (OR 177, 95% CI 105-298, P=003) were associated with infection but not with the development of OT. Age (OT 482 +/- 212 years vs. OOD: 695 +/- 147 years, P<00001) and the low level of schooling/literacy (OT vs. OOD: OR 0414, 95% CI 02231-07692, P=0007) were associated with OT. The presence of dogs and cats as well as eating raw/undercooked meat increases the risk of infection, but is not associated with the development of OT. (AU) | |
| FAPESP's process: | 11/13939-8 - Study of a group of fungal and parasitic infections aiming the improvement of techniques of characterization and immune-molecular diagnosis |
| Grantee: | Vera Lúcia Pereira Chioccola |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 09/09168-6 - Toxoplasma gondii excreted-secreted antigens (ESA): Analysis of infected host immune response |
| Grantee: | Cristina da Silva Meira Strejevitch |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 12/07750-2 - Serological and molecular investigation of Toxoplasma gondii in blood donors |
| Grantee: | Fabiana Nakashima |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 09/17540-2 - Histo blood groups like risk factor for ocular toxoplasmosis |
| Grantee: | Luiz Carlos de Mattos |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 12/05580-2 - Immunogenetics markers in Chagas disease |
| Grantee: | Cássia Rubia Bernardo |
| Support Opportunities: | Scholarships in Brazil - Master |