Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Sub-2 mu m fully porous and partially porous (core-shell) stationary phases for reversed phase liquid chromatography

Full text
Author(s):
Borges, Endler M. [1] ; Rostagno, Mauricio A. [2] ; Meireles, M. Angela A. [2]
Total Authors: 3
Affiliation:
[1] Univ Oeste Santa Catarina UNOESC, Nucleo Biotecnol, BR-89560000 Videira, SC - Brazil
[2] Univ Campinas UNICAMP, Sch Food Engn, Dept Food Engn, LASEFI, BR-13083862 Campinas, SP - Brazil
Total Affiliations: 2
Document type: Review article
Source: RSC ADVANCES; v. 4, n. 44, p. 22875-22887, 2014.
Web of Science Citations: 17
Abstract

The need for increased throughput and superior performance has increased the demand for stationary phases with improved kinetic performance. Among them, increasing the sample throughput of the ever-growing number of necessary (routine) analyses has become a popular target for reducing precious time. For the past thirty years, high-performance liquid chromatography (HPLC) has been the leading technology when it comes to various analyses; however, the requirement of typically 10-45 min for serial analyses has been a sample throughput-limiting barrier. Recently, the fundamentals of HPLC have been exploited to develop new technologies that can speed up analyses to ground-breaking limits without compromising separation efficiency. This paper reviews the most promising technologies, including porous sub-2 mm ultra-performance liquid chromatography (UPLC) and fused-core particle technology, which have the potential to take LC to the next level. As each analytical method has its own demands, the advances of the above mentioned technologies are discussed for different applications where high throughput analysis can be meaningful. Moreover, we discuss and compare the perspectives of these technologies. (AU)

FAPESP's process: 13/04304-4 - Development of integrated systems for the analysis of bioactive compounds in natural products employing supercritical technology
Grantee:Maurício Ariel Rostagno
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 12/10685-8 - Combination and coupling of processes for the production and encapsulation of value-added vegetal extracts: technical and economic evaluation
Grantee:Maria Angela de Almeida Meireles Petenate
Support Opportunities: Regular Research Grants
FAPESP's process: 13/15049-5 - Development of integrated systems for the analysis of bioactive compounds in natural products employing supercritical technology
Grantee:Maurício Ariel Rostagno
Support Opportunities: Scholarships in Brazil - Young Researchers
FAPESP's process: 11/07466-0 - Determination of avermectins, milbemycins and amphenicols in fish filet: using LC-MS/MS
Grantee:Endler Marcel Borges de Souza
Support Opportunities: Scholarships in Brazil - Post-Doctoral