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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Improved synthesis of bioactive stilbene derivatives applying design of experiments to the Heck-Matsuda reaction

Full text
Author(s):
Perez, Carla Cristina [1] ; Pena, Jesus Marcelo [1] ; Duarte Correia, Carlos Roque [1]
Total Authors: 3
Affiliation:
[1] Univ Estadual Campinas, UNICAMP, Inst Chem, BR-13084971 Campinas, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: NEW JOURNAL OF CHEMISTRY; v. 38, n. 8, p. 3933-3938, AUG 2014.
Web of Science Citations: 8
Abstract

Design of experiments was employed to optimize the reaction conditions used to synthesize stilbene derivatives. New Heck conditions were tested using several styrenes and aryldiazonium tetrafluoroborates, generating the desired stilbenes in good yields in all cases under very practical, economical and effective conditions. This methodology was used for the synthesis of bioactive stilbenes such as resveratrol, DMU-212, and their analogues. (AU)

FAPESP's process: 11/23832-6 - New methodological and mechanistic studies related to the Heck arylations employing arenediazonium salts and synthetic applications
Grantee:Carlos Roque Duarte Correia
Support Opportunities: Regular Research Grants
FAPESP's process: 12/07461-0 - Study of Heck Arilation applying Arenediazonium Salts in the synthesis of hydroxy stilbenos and derivatives.
Grantee:Carla Cristina Perez
Support Opportunities: Scholarships in Brazil - Post-Doctoral