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Identification and chemical characterization of bioactive and nanostructured fraction of geopropolis (Melipona scutellaris) and their related pharmacological activities

Grant number: 10/20214-7
Support Opportunities:Regular Research Grants
Start date: March 01, 2011
End date: February 28, 2013
Field of knowledge:Health Sciences - Dentistry - Social and Preventive Dentistry
Principal Investigator:Pedro Luiz Rosalen
Grantee:Pedro Luiz Rosalen
Host Institution: Faculdade de Odontologia de Piracicaba (FOP). Universidade Estadual de Campinas (UNICAMP). Piracicaba , SP, Brazil
Associated researchers:Carina Denny ; Marcelo Henrique Napimoga ; Marlus Chorilli ; Masaharu Ikegaki ; Miriam Elias Cavallini ; Severino Matias de Alencar
Articles published in Agência FAPESP Newsletter about the research grant:
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (8)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FRANCHIN, MARCELO; DA CUNHA, MARCOS GUILHERME; DENNY, CARINA; NAPIMOGA, MARCELO HENRIQUE; CUNHA, THIAGO MATTAR; KOO, HYUN; DE ALENCAR, SEVERINO MATIAS; IKEGAKI, MASAHARU; ROSALEN, PEDRO LUIZ. Geopropolis from Melipona scutellaris decreases the mechanical inflammatory hypernociception by inhibiting the production of IL-1 beta and TNF-alpha. Journal of Ethnopharmacology, v. 143, n. 2, p. 709-715, . (10/20214-7, 09/12352-3)
DA CUNHA, MARCOS GUILHERME; FRANCHIN, MARCELO; DE CARVALHO GALVAO, LIVIA CAMARA; TASCA GOIS DE RUIZ, ANA LUCIA; DE CARVALHO, JOAO ERNESTO; IKEGAKI, MASARAHU; DE ALENCAR, SEVERINO MATIAS; KOO, HYUN; ROSALEN, PEDRO LUIZ. Antimicrobial and antiproliferative activities of stingless bee Melipona scutellaris geopropolis. BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, v. 13, . (10/20214-7, 09/12354-6)
DA CUNHA, MARCOS GUILHERME; FRANCHIN, MARCELO; DE CARVALHO GALVAO, LIVIA CAMARA; BUENO-SILVA, BRUNO; IKEGAKI, MASAHARU; DE ALENCAR, SEVERINO MATIAS; ROSALEN, PEDRO LUIZ. Apolar Bioactive Fraction of Melipona scutellaris Geopropolis on Streptococcus mutans Biofilm. Evidence-based Complementary and Alternative Medicine, v. 2013, p. 7-pg., . (13/10879-0, 09/12354-6, 10/20214-7)
FRANCHIN, MARCELO; DA CUNHA, MARCOS GUILHERME; DENNY, CARINA; NAPIMOGA, MARCELO HENRIQUE; CUNHA, THIAGO MATTAR; BUENO-SILVA, BRUNO; DE ALENCAR, SEVERINO MATIAS; IKEGAKI, MASAHARU; ROSALEN, PEDRO LUIZ. Bioactive Fraction of Geopropolis from Melipona scutellaris Decreases Neutrophils Migration in the Inflammatory Process: Involvement of Nitric Oxide Pathway. Evidence-based Complementary and Alternative Medicine, v. 2013, p. 9-pg., . (09/12352-3, 10/20214-7)
RIBEIRO-JUNIOR, JERONIMO APARECIDO; FRANCHIN, MARCELO; CAVALLINI, MIRIAM ELIAS; DENNY, CARINA; DE ALENCAR, SEVERINO MATIAS; IKEGAKI, MASAHARU; ROSALEN, PEDRO LUIZ. Gastroprotective Effect of Geopropolis from Melipona scutellaris Is Dependent on Production of Nitric Oxide and Prostaglandin. Evidence-based Complementary and Alternative Medicine, . (10/20214-7)
FRANCHIN, MARCELO; DA CUNHA, MARCOS GUILHERME; DENNY, CARINA; NAPIMOGA, MARCELO HENRIQUE; CUNHA, THIAGO MATTAR; BUENO-SILVA, BRUNO; DE ALENCAR, SEVERINO MATIAS; IKEGAKI, MASAHARU; ROSALEN, PEDRO LUIZ. Bioactive Fraction of Geopropolis from Melipona scutellaris Decreases Neutrophils Migration in the Inflammatory Process: Involvement of Nitric Oxide Pathway. Evidence-based Complementary and Alternative Medicine, . (10/20214-7, 09/12352-3)
DA CUNHA, MARCOS GUILHERME; FRANCHIN, MARCELO; DE CARVALHO GALVAO, LIVIA CAMARA; BUENO-SILVA, BRUNO; IKEGAKI, MASAHARU; DE ALENCAR, SEVERINO MATIAS; ROSALEN, PEDRO LUIZ. Apolar Bioactive Fraction of Melipona scutellaris Geopropolis on Streptococcus mutans Biofilm. Evidence-based Complementary and Alternative Medicine, . (10/20214-7, 09/12354-6, 13/10879-0)
RIBEIRO-JUNIOR, JERONIMO APARECIDO; FRANCHIN, MARCELO; CAVALLINI, MIRIAM ELIAS; DENNY, CARINA; DE ALENCAR, SEVERINO MATIAS; IKEGAKI, MASAHARU; ROSALEN, PEDRO LUIZ. Gastroprotective Effect of Geopropolis from Melipona scutellaris Is Dependent on Production of Nitric Oxide and Prostaglandin. Evidence-based Complementary and Alternative Medicine, v. 2015, p. 5-pg., . (10/20214-7)